4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate

Base Information

• Chemical Name: 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate
• CAS No.: 85063-77-0
• Molecular Formula: C₁₈H₂₂N₄*H₂O₄S
• Molecular Weight: 392.479
• Mol file: 85063-77-0.mol

Synonyms:

Chemical Property of 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate

There total 3 articles about 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenylmethylpiperazine (841-77-0) → 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate (85063-77-0)

Guidance literature:

With ethanol; 2-methyl-2-thiopseudouronium sulfate;

DOI:10.1021/ja01176a038

Reference yield:

1-benzhydryl-4-(ethoxycarbonyl)piperazine (102552-76-1) → 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate (85063-77-0)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic KOH

2: S-methyl-thiuronium-sulfate; aqueous ethanol

With potassium hydroxide; ethanol; 2-methyl-2-thiopseudouronium sulfate;

DOI:10.1021/ja01176a038

Reference yield:

Bromodiphenylmethane (776-74-9) → 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate (85063-77-0)

Guidance literature:

Multi-step reaction with 3 steps

1: Na₂CO₃

2: ethanolic KOH

3: S-methyl-thiuronium-sulfate; aqueous ethanol

With potassium hydroxide; ethanol; sodium carbonate; 2-methyl-2-thiopseudouronium sulfate;

DOI:10.1021/ja01176a038

upstream raw materials:

diphenylmethylpiperazine

1-benzhydryl-4-(ethoxycarbonyl)piperazine

Bromodiphenylmethane