1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene

Base Information

• Chemical Name: 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene
• CAS No.: 113795-30-5
• Molecular Formula: C₁₉H₂₃BrO
• Molecular Weight: 347.295
• Mol file: 113795-30-5.mol

Synonyms:

Chemical Property of 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene

There total 6 articles about 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(p-methoxyphenyl)-4-phenylbutane (38841-95-1) → 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene (113795-30-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine hydrochloride / 4 h / 200 °C

2: NaH / tetrahydrofuran / 8 h / Heating

With pyridine hydrochloride; sodium hydride; In tetrahydrofuran;

DOI:10.1021/jm00401a022

Reference yield:

1-(4-methoxyphenyl)-4-phenylbutan-1-one (101594-58-5) → 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene (113795-30-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 80percent hydrazine hydrate, 0.66 mol NaOH / bis-(2-hydroxy-ethyl) ether / 4 h / Heating

2: pyridine hydrochloride / 4 h / 200 °C

3: NaH / tetrahydrofuran / 8 h / Heating

With sodium hydroxide; pyridine hydrochloride; sodium hydride; hydrazine hydrate; In tetrahydrofuran; diethylene glycol;

DOI:10.1021/jm00401a022

Reference yield:

methoxybenzene (100-66-3) → 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene (113795-30-5)

Guidance literature:

Multi-step reaction with 4 steps

1: AlCl₃ / 1 h / Ambient temperature

2: 80percent hydrazine hydrate, 0.66 mol NaOH / bis-(2-hydroxy-ethyl) ether / 4 h / Heating

3: pyridine hydrochloride / 4 h / 200 °C

4: NaH / tetrahydrofuran / 8 h / Heating

With sodium hydroxide; aluminium trichloride; pyridine hydrochloride; sodium hydride; hydrazine hydrate; In tetrahydrofuran; diethylene glycol;

DOI:10.1021/jm00401a022

upstream raw materials:

p-(4-phenylbutyl)phenol

1,3-dibromo-propane

1-(p-methoxyphenyl)-4-phenylbutane

1-(4-methoxyphenyl)-4-phenylbutan-1-one

Downstream raw materials:

2,2-Dimethyl-5-[4-(4-phenyl-butyl)-phenoxy]-pentanoic acid