38841-95-1

Basic information

• Product Name: Benzene, 1-methoxy-4-(4-phenylbutyl)-
• CAS NO: 38841-95-1
• Molecular Formula: C17H20O
• Molecular Weight: 240.345
• Mol File: 38841-95-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-4-(4-phenylbutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-4-(4-phenylbutyl)-(38841-95-1)
• EPA Substance Registry System: Benzene, 1-methoxy-4-(4-phenylbutyl)-(38841-95-1)

Safety Data

• Hazardous Substances Data: 38841-95-1(Hazardous Substances Data)

Upstream product

• 100-66-3 methoxybenzene 
• 18496-54-3 phenylbutyric acid chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 108-86-1 bromobenzene 
• 52244-70-9 4-(4-methoxyphenyl)butan-1-ol 
• 64283-87-0 4-phenyl-1-iodobutane 
• 696-62-8 para-iodoanisole 
• 39110-26-4 (triphenylphosphonio)-3-phenyl-1-propanide 
• 1821-12-1 4-Phenylbutyric acid 
• 150660-28-9 1-methoxy-4-(4-phenyl-but-1-enyl)-benzene 
• 101594-58-5 1-(4-methoxyphenyl)-4-phenylbutan-1-one 
• 66107-29-7 4-methoxyphenyl triflate 
• 81012-82-0 (2-bromobutyl)benzene 
• 701-70-2 1-phenyl-2-butanol 

Downstream Products

• 113795-27-0 5-Methyl-4-oxy-pyrazine-2-carboxylic acid 2,2-dimethyl-6-[4-(4-phenyl-butyl)-phenoxy]-hexyl ester 
• 113795-24-7 2,2-Dimethyl-6-[4-(4-phenyl-butyl)-phenoxy]-hexanoic acid 5-methyl-pyrazin-2-ylmethyl ester 
• 113795-26-9 5-Methyl-pyrazine-2-carboxylic acid 2,2-dimethyl-6-[4-(4-phenyl-butyl)-phenoxy]-hexyl ester 
• 113795-23-6 2,2-Dimethyl-6-[4-(4-phenyl-butyl)-phenoxy]-hexanoic acid pyridin-3-ylmethyl ester 
• 113795-25-8 Nicotinic acid 2,2-dimethyl-6-[4-(4-phenyl-butyl)-phenoxy]-hexyl ester 
• 113795-20-3 2,2-Dimethyl-12-[4-(4-phenyl-butyl)-phenoxy]-dodecanoic acid 
• 113795-19-0 2,2-Dimethyl-11-[4-(4-phenyl-butyl)-phenoxy]-undecanoic acid 
• 113795-18-9 2,2-Dimethyl-10-[4-(4-phenyl-butyl)-phenoxy]-decanoic acid 
• 113795-39-4 1-(10-Bromo-decyloxy)-4-(4-phenyl-butyl)-benzene 
• 113810-77-8 1-(9-Bromo-nonyloxy)-4-(4-phenyl-butyl)-benzene 
• 113795-17-8 2,2-Dimethyl-9-[4-(4-phenyl-butyl)-phenoxy]-nonanoic acid 
• 113795-16-7 2,2-Dimethyl-8-[4-(4-phenyl-butyl)-phenoxy]-octanoic acid 
• 113795-38-3 1-(8-Bromo-octyloxy)-4-(4-phenyl-butyl)-benzene 
• 113795-53-2 2,2-dimethyl-6-<4-(4-phenylbutyl)phenoxy>hexanol 

Relevant articles and documents

Electrochemically Enabled, Nickel-Catalyzed Dehydroxylative Cross-Coupling of Alcohols with Aryl Halides

As alcohols are ubiquitous throughout chemical science, this functional group represents a highly attractive starting material for forging new C-C bonds. Here, we demonstrate that the combination of anodic preparation of the alkoxy triphenylphosphonium ion and nickel-catalyzed cathodic reductive cross-coupling provides an efficient method to construct C(sp2)-C(sp3) bonds, in which free alcohols and aryl bromides - both readily available chemicals - can be directly used as coupling partners. This nickel-catalyzed paired electrolysis reaction features a broad substrate scope bearing a wide gamut of functionalities, which was illustrated by the late-stage arylation of several structurally complex natural products and pharmaceuticals.

Terminal-Selective Functionalization of Alkyl Chains by Regioconvergent Cross-Coupling

Hydrocarbons are still the most important precursors of functionalized organic molecules, which has stirred interest in the discovery of new C?H bond functionalization methods. We describe herein a new step-economical approach that enables C?C bonds to be constructed at the terminal position of linear alkanes. First, we show that secondary alkyl bromides can undergo in situ conversion into alkyl zinc bromides and regioconvergent Negishi coupling with aryl or alkenyl triflates. The use of a suitable phosphine ligand favoring Pd migration enabled the selective formation of the linear cross-coupling product. Subsequently, mixtures of secondary alkyl bromides were prepared from linear alkanes by standard bromination, and regioconvergent cross-coupling then provided access to the corresponding linear arylation product in only two steps.

Synthesis and Hypolipidemic Activity of 2-Substituted Isobutyric Acid Derivatives

A series of 2-substituted isobutyric acid derivatives have been synthesized and evaluated as hypolipidemic agents.Compounds 11 and 20 were found to decrease the level of plasma total cholesterol in experimental hyperlipidemic rats to a greater extent than clofibrate (CF) and to increase the level of plasma high-density lipoprotein cholesterol to the same extent as gemfibrozil (GF).Increase in liver weight caused by these compounds were less than those with CF and GF.