methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate

Base Information

• Chemical Name: methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate
• CAS No.: 74074-88-7
• Molecular Formula: C₁₂H₁₆O₂S₃
• Molecular Weight: 288.456
• Mol file: 74074-88-7.mol

Synonyms:

Chemical Property of methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate

There total 3 articles about methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(isopropylthio)-4-methylbenzene (14905-81-8) → methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate (74074-88-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 30percent H₂O₂ / acetic acid

2: 1.) BuLi / 1.) hexane, THF, from -78 deg C to room temperature, 2.) hexane, THF, room temperature, 1h

With n-butyllithium; dihydrogen peroxide; In acetic acid;

Reference yield:

para-thiocresol (106-45-6) → methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate (74074-88-7)

Guidance literature:

Multi-step reaction with 3 steps

2: 30percent H₂O₂ / acetic acid

3: 1.) BuLi / 1.) hexane, THF, from -78 deg C to room temperature, 2.) hexane, THF, room temperature, 1h

With n-butyllithium; dihydrogen peroxide; In acetic acid;

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 1-methyl-4-(propane-2-sulfonyl)benzene (51751-71-4,20288-47-5) + methyl iodide (74-88-4) → methyl 2-methyl-2-(p-tolylsulfonyl)propanedithioate (74074-88-7)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) hexane, THF, from -78 deg C to room temperature, 2.) hexane, THF, room temperature, 1h;

upstream raw materials:

carbon disulfide

1-methyl-4-(propane-2-sulfonyl)benzene

methyl iodide

1-(isopropylthio)-4-methylbenzene

Downstream raw materials:

<2-(p-tolylsulfonyl)-2-propyl>(methylthio)sulfine

Refernces