(1-Anilinocyclopropyl)-phenyl-amine

Base Information

• Chemical Name: (1-Anilinocyclopropyl)-phenyl-amine
• CAS No.: 6246-99-7
• Molecular Formula: C₁₅H₁₆N₂
• Molecular Weight: 224.305
• DSSTox Substance ID: DTXSID401288166
• Nikkaji Number: J408.384I
• Mol file: 6246-99-7.mol

Synonyms:(1-anilinocyclopropyl)-phenyl-amine;DTXSID401288166;N,N'-diphenylcyclopropane-1,1-diamine;6246-99-7

Chemical Property of (1-Anilinocyclopropyl)-phenyl-amine

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 224.131348519
• Heavy Atom Count: 17
• Complexity: 213

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC1(NC2=CC=CC=C2)NC3=CC=CC=C3

Technology Process of (1-Anilinocyclopropyl)-phenyl-amine

There total 3 articles about (1-Anilinocyclopropyl)-phenyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

1,2-propanediene (463-49-0) + Phenyl azide (622-37-7) → 4-benzyl-1-(4-fluorophenyl)-1H-1,2,3-triazole (20320-20-1) + 1,1-Dianilinocyclopropane (6246-99-7) + 5-methyl-1-phenyl-1H-1,2,3-triazole (6111-96-2)

Guidance literature:

In benzene; at 100 ℃; 3 weeks;

DOI:10.1021/jo00014a026

Reference yield:

1-ethoxy-1-cyclopropanol (13837-45-1) + aniline (62-53-3) → 1,1-Dianilinocyclopropane (6246-99-7)

Guidance literature:

at 25 ℃;

DOI:10.1021/ja00974a088

Reference yield:

methanol (67-56-1) + [(1-Ethoxycyclopropyl)oxy]trimethylsilane (27374-25-0) + aniline (62-53-3) → 1,1-Dianilinocyclopropane (6246-99-7) + (1-methoxy-cyclopropyl)-phenyl-amine

Guidance literature:

With acetic acid; at 67 - 69 ℃; for 5h; Title compound not separated from byproducts;

DOI:10.1055/s-2003-42072

upstream raw materials:

1,2-propanediene

Phenyl azide

1-ethoxy-1-cyclopropanol

aniline