Technology Process of Dibromobis(2,4,6-trimethylphenyl)germane
There total 2 articles about Dibromobis(2,4,6-trimethylphenyl)germane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen bromide;
In
water; benzene;
addn. of a soln. of acid in H2O to a soln. of germane in benzene (N2), stirring for 2 h at 60°C; extn. with pentane, drying over Na2SO4, evapn. (reduced pressure), recrystn. in pentane; elem. anal.;
DOI:10.1021/ja00236a016
- Guidance literature:
-
With
ammonium hydroxide;
In
tetrahydrofuran;
N2 or Ar; aq. NH4OH addn. dropwise to Ge-compd. soln. (THF), stirring 30min at 20°C, org. phase sepn. from. aq. phase, aq. phase extn. t wice with benzene, drying (Na2SO4), HBr addn. at 5°C, org. phase recuperationm drying (Na2SO4); solvent evapn. to dryness, recrystn. (pentane);
DOI:10.1080/10426509608046364
- Guidance literature:
-
With
tert.-butyl lithium;
In
tetrahydrofuran; diethyl ether; pentane;
byproducts: LiBr; inert atmosphere; stirring equimolar amts. of Ge-compd. and sulfonamide (in THF, room temp., 1 h), solvent removal, dissoln. in Et2O, cooling to-78°C, dropwise addn. of equimolar amt. of t-BuLi, slow warming to room temp. over 4 h; addn. of C6H6, centrifugation off of LiBr, evapn. (vac.);
DOI:10.1016/S0022-328X(97)00449-X
