2-(2-pyridyl)phosphaethene

Base Information

• Chemical Name: 2-(2-pyridyl)phosphaethene
• CAS No.: 144404-03-5
• Molecular Formula: C₂₄H₃₄NP
• Molecular Weight: 367.514
• Mol file: 144404-03-5.mol

Synonyms:

Chemical Property of 2-(2-pyridyl)phosphaethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-pyridyl)phosphaethene

There total 1 articles about 2-(2-pyridyl)phosphaethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine-2-carbaldehyde (1121-60-4) + (2,4,6-tri-tert-butylphenyl)phosphine (83115-12-2) → 2-(2,4,6-Tri-tert-butyl-phenylphosphanylidenemethyl)-pyridine (144404-03-5,144404-05-7,600179-11-1)

Guidance literature:

With n-butyllithium; tert-butyldimethylsilyl chloride; In tetrahydrofuran; for 1h; Ambient temperature;

DOI:10.1016/S0040-4039(00)61192-9

Reference yield: 90.0%

chloromethyl(1,5-cyclooctadiene)palladium(II) + (E)-((2-pyridyl)methylene)(2,4,6-tri-tert-butylphenyl)phosphine (144404-03-5,600179-11-1,144404-05-7) → η(1),η(1)-[(E)-((2-pyridyl)methylene)(2,4,6-tri-tert-butylphenyl)phosphine]methylpalladium chloride (186688-46-0)

Guidance literature:

In dichloromethane; N2-atmosphere; stirring (room temp., 10 min); evapn. (reduced pressure), washing (ether / pentane), drying (vac.); elem. anal.;

DOI:10.1021/om960925g

Reference yield: 86.0%

bis(2-phenylpyridine-C2,N)-bis(aquo)iridium(III) trifluoromethanesulfonate (153297-46-2) + 2-(2-pyridyl)phosphaethene (144404-03-5,144404-05-7,600179-11-1) → Ir(2-pyridylphenyl)2(2-(2-pyridyl)phosphaethene)OTf (864358-25-8)

Guidance literature:

In dichloromethane; (under N2, Schlenk); ligand added to soln. of Ir-complex in CH2Cl2 with stirring, stirred at room temp. for 2 h; volatiles removed under reduced pressure, residue washed with Et2O, hexane at 0°C, dried under reduced pressure; elem. anal.;

DOI:10.1021/om700275s

upstream raw materials:

pyridine-2-carbaldehyde

(2,4,6-tri-tert-butylphenyl)phosphine

Downstream raw materials:

η(1),η(1)-[(E)-((2-pyridyl)methylene)(2,4,6-tri-tert-butylphenyl)phosphine]methylpalladium chloride

η(1),η(1)-[(E)-((2-pyridyl)methylene)(2,4,6-tri-tert-butylphenyl)phosphine]palladium dichloride

η(1),η(1)-[(E)-((2-pyridyl)methylene)(2,4,6-tri-tert-butylphenyl)phosphine]acetylpalladium chloride

Ir(2-pyridylphenyl)2(2-(2-pyridyl)phosphaethene)OTf

Refernces