(2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid

Base Information Edit

Chemical Name:(2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid
CAS No.:14752-56-8
Molecular Formula:C₁₁H₁₉NO₉
Molecular Weight:309.273
Hs Code.:
Mol file:14752-56-8.mol

Synonyms:

Suppliers and Price of (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid Edit

Chemical Property:

Vapor Pressure:5.5E-30mmHg at 25°C

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid

There total 19 articles about (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 131-48-6,14752-56-8,5977-25-3,6225-16-7,6918-20-3
N-Acetylneuraminic acid

Guidance literature:

Reference yield:

: 5-(1-acetylamino-2,3,4,5-tetrahydroxy-pentyl)-2-tert-butyl-isoxazolidine-3-carboxylic acid ethyl ester

: 131-48-6,14752-56-8,5977-25-3,6225-16-7,6918-20-3
N-Acetylneuraminic acid

Guidance literature:: 5-(1-acetylamino-2,3,4,5-tetrahydroxy-pentyl)-2-tert-butyl-isoxazolidine-3-carboxylic acid ethyl ester; With sodium methylate; In methanol; at 20 ℃;

With water; for 24h;
DOI:10.1002/anie.200601555

Reference yield:

: 5-amino-hept-6-ene-1,2,3,4-tetraol

: 131-48-6,14752-56-8,5977-25-3,6225-16-7,6918-20-3
N-Acetylneuraminic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydrogen carbonate / methanol / 1 h

2.1: dioxane / 336 h / 30 °C

3.1: NaOMe / methanol / 20 °C

3.2: water / 24 h

With sodium methylate; sodium hydrogencarbonate; In 1,4-dioxane; methanol;
DOI:10.1002/anie.200601555