2,3,4,6-Tetrafluorobenzotrifluoride

Base Information

• Chemical Name: 2,3,4,6-Tetrafluorobenzotrifluoride
• CAS No.: 5360-82-7
• Molecular Formula: C7H F7
• Molecular Weight: 218.07
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID70382143
• Nikkaji Number: J736.227G
• Wikidata: Q82173458
• Mol file: 5360-82-7.mol

Synonyms:2,3,4,6-Tetrafluorobenzotrifluoride;5360-82-7;1,2,3,5-tetrafluoro-4-(trifluoromethyl)benzene;3h-heptafluorotoluene;1,2,3,5-Tetrafluoro-4-trifluoromethyl-benzene;MFCD00190111;SCHEMBL9507060;DTXSID70382143;2,3,4,6-tetrafluorbenzotrifluoride;2,3,4,6-tetrafluoro-benzotrifluoride;AKOS017344339;FT-0635645;A829679

Chemical Property of 2,3,4,6-Tetrafluorobenzotrifluoride

Chemical Property:

• Vapor Pressure: 30.6mmHg at 25°C
• Refractive Index: 1.3776
• Boiling Point: 109-110
• Flash Point: 18°C
• PSA: 0.00000
• Density: 1.56g/cm³
• LogP: 3.26180
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 0
• Exact Mass: 217.99664717
• Heavy Atom Count: 14
• Complexity: 201

Purity/Quality:

98%Min ^*data from raw suppliers

SG000423:1,2,3,5-Tetrafluoro-4-trifluoromethyl-benzene 98 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=C(C(=C1F)F)F)C(F)(F)F)F

Technology Process of 2,3,4,6-Tetrafluorobenzotrifluoride

There total 6 articles about 2,3,4,6-Tetrafluorobenzotrifluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzene (4284-09-7) → 4-trifluoromethyl-1,2,3,5-tetrafluorobenzene (5360-82-7) + 1-bromo-2,3,4,6-tetrafluoro-5-(trifluoromethyl)benzene (5360-80-5)

Guidance literature:

1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzene; With 2-H-3-chlorohexafluorotoluene; zinc; In N,N-dimethyl-formamide; at 70 ℃; for 8h; closed flask;

With bromine; N,N-dimethyl-formamide; steam distillation;

DOI:10.1070/MC2006v016n03ABEH002266

Reference yield:

1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzene (4284-09-7) → 4-trifluoromethyl-1,2,3,5-tetrafluorobenzene (5360-82-7) + 1-chloro-2,4,5-trifluoro-3-(trifluoromethyl)benzene (122030-03-9)

Guidance literature:

1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzene; With 2-H-3-chlorohexafluorotoluene; tin(ll) chloride; zinc; In N,N-dimethyl-formamide; at 70 ℃; for 8h; closed flask;

With hydrogenchloride; In N,N-dimethyl-formamide;

DOI:10.1070/MC2006v016n03ABEH002266

Reference yield:

1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzene (4284-09-7) → 1-bromo-2-chloro-3,5,6-trifluoro-4-(trifluoromethyl)benzene + 4-trifluoromethyl-1,2,3,5-tetrafluorobenzene (5360-82-7) + 1-bromo-2,3,4,6-tetrafluoro-5-(trifluoromethyl)benzene (5360-80-5) + 1-chloro-2,4,5-trifluoro-3-(trifluoromethyl)benzene (122030-03-9)

Guidance literature:

1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzene; With 2-H-3-chlorohexafluorotoluene; tin(ll) chloride; zinc; In N,N-dimethyl-formamide; at 70 ℃; for 27h; closed flask;

With bromine; N,N-dimethyl-formamide; steam distillation;

DOI:10.1070/MC2006v016n03ABEH002266

upstream raw materials:

1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzene

3-chloroprop-1-ene

Refernces

• 1、 Krasnov, Vyacheslav I.,Vinogradov, Andrey S.,Platonov, Vyacheslav E.. "Preparation of organozinc compounds from 3-chloroheptafluorotoluene and zinc: The participation of C-F bonds". . p. 168 - 170. Retrieved 2007/10/03.