2-Oxo-6-phenylhexa-3,5-dienoic acid

Base Information

Chemical Name:2-Oxo-6-phenylhexa-3,5-dienoic acid
CAS No.:4403-24-1
Molecular Formula:C12H10 O3
Molecular Weight:202.206
Hs Code.:
NSC Number:405818
DSSTox Substance ID:DTXSID60419699
Nikkaji Number:J1.828.577K,J76.671B,J2.454.034K
Wikidata:Q82230859

Synonyms:4403-24-1;NSC405818;2-oxo-6-phenylhexa-3,5-dienoic acid;Cinnamylidenepyruvic acid;SCHEMBL559826;DTXSID60419699;6-Phenyl-2-oxo-3,5-hexadienoic acid;NSC-405818;(3E,5E)-2-Oxo-6-phenyl-3,5-hexadienoic acid

Suppliers and Price of 2-Oxo-6-phenylhexa-3,5-dienoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Oxo-6-phenylhexa-3,5-dienoic acid

Chemical Property:

Vapor Pressure:6.77E-06mmHg at 25°C
Boiling Point:362.7°C at 760 mmHg
Flash Point:187.3°C
Density:1.223g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:202.062994177
Heavy Atom Count:15
Complexity:283

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C=CC=CC(=O)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)/C=C/C=C/C(=O)C(=O)O

Technology Process of 2-Oxo-6-phenylhexa-3,5-dienoic acid

There total 9 articles about 2-Oxo-6-phenylhexa-3,5-dienoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 14371-10-9
(E)-3-phenylpropenal

: 127-17-3
2-oxo-propionic acid

: 4403-24-1
(3E,5E)-2-oxo-6-phenylhexa-3,5-dienoic acid

Guidance literature:: With potassium hydroxide; In methanol; at 40 ℃;
DOI:10.1016/S0040-4020(01)86506-6

Reference yield:

: 14371-10-9
(E)-3-phenylpropenal

: 113-24-6
sodium pyruvate

: 4403-24-1
(3E,5E)-2-oxo-6-phenylhexa-3,5-dienoic acid

Guidance literature:: With potassium hydroxide; In methanol; water; at 0 - 10 ℃;
DOI:10.1016/j.tet.2007.02.099

Reference yield:

: 100-52-7
benzaldehyde

: 4403-24-1
(3E,5E)-2-oxo-6-phenylhexa-3,5-dienoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Ba(OH)2 / tetrahydrofuran / 70 °C

2: KOH / methanol; H₂O / 0 - 10 °C

With barium dihydroxide; potassium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1016/j.tet.2007.02.099