cis, cis-1-formyl-2,3-diphenylcyclopropane

Base Information

• Chemical Name: cis, cis-1-formyl-2,3-diphenylcyclopropane
• CAS No.: 102519-32-4
• Molecular Formula: C₁₆H₁₄O
• Molecular Weight: 222.287
• Mol file: 102519-32-4.mol

Synonyms:

Chemical Property of cis, cis-1-formyl-2,3-diphenylcyclopropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis, cis-1-formyl-2,3-diphenylcyclopropane

There total 8 articles about cis, cis-1-formyl-2,3-diphenylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cis, trans-1-hydroxymethyl-2,3-diphenylcyclopropane (7381-90-0,7381-98-8,26848-96-4) → trans-2,3-diphenylcyclopropane-1-carbaldehyde (52456-99-2,64200-26-6,102519-32-4)

Guidance literature:

cis, trans-1-hydroxymethyl-2,3-diphenylcyclopropane; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 1h; Inert atmosphere;

With triethylamine; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/c9ob00359b

Reference yield: 71.0%

((1R*,2R*)-3-bromocyclopropane-1,2-diyl)dibenzene (61608-79-5) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → trans-2,3-diphenylcyclopropane-1-carbaldehyde (52456-99-2,64200-26-6,102519-32-4)

Guidance literature:

((1R*,2R*)-3-bromocyclopropane-1,2-diyl)dibenzene; With TurboGrignard; In tetrahydrofuran; 1,4-dioxane; at -16 ℃; for 14h;

N,N-dimethyl-formamide; In tetrahydrofuran; 1,4-dioxane; stereoselective reaction;

DOI:10.1055/s-0028-1087487

Reference yield: 62.0%

cis, cis-1-hydroxymethyl-2,3-diphenylcyclopropane (7381-90-0) → cis, cis-1-formyl-2,3-diphenylcyclopropane (102519-32-4)

Guidance literature:

With chromium trioxide pyridine; In dichloromethane;

upstream raw materials:

acid chloride of cis, trans-2,3-diphenylcyclopropanecarboxylic acid

ethyl ester of (racemic) 2,3-diphenylcyclopropane-1-carboxylic acid

((1R*,2R*)-3-bromocyclopropane-1,2-diyl)dibenzene

N,N-dimethyl-formamide

Downstream raw materials:

2-phenylnaphthalene

(1Z,3Z)-1,4-diphenylbuta-1,3-diene

trans-1,2,3-triphenylcyclopropane