Technology Process of Benzyl bis(pivaloyloxymethoxy)phosphorylacetate
There total 3 articles about Benzyl bis(pivaloyloxymethoxy)phosphorylacetate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 84 percent / Me3SiBr / acetonitrile / 3 h / Ambient temperature
2: 1) AgNO3 / 1) MeOH, water, 0-5 deg C, 15 min, 2) toluene, a) -78 deg, 4 h, b) r.t., 18 h
With
trimethylsilyl bromide; silver nitrate;
In
acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 70 percent / iPr2NEt, 4-N,N-dimethylaminopyridine / acetonitrile / 5 h / Ambient temperature
2: 84 percent / Me3SiBr / acetonitrile / 3 h / Ambient temperature
3: 1) AgNO3 / 1) MeOH, water, 0-5 deg C, 15 min, 2) toluene, a) -78 deg, 4 h, b) r.t., 18 h
With
dmap; trimethylsilyl bromide; silver nitrate; N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
- Guidance literature:
-
With
silver nitrate;
Yield given. Multistep reaction;
1) MeOH, water, 0-5 deg C, 15 min, 2) toluene, a) -78 deg, 4 h, b) r.t., 18 h;
