ethyl(S)-4-benzyloxy-3-hydroxybutyrate

Base Information

Chemical Name:ethyl(S)-4-benzyloxy-3-hydroxybutyrate
CAS No.:112348-04-6
Molecular Formula:C13H18O4
Molecular Weight:238.284
Hs Code.:
DSSTox Substance ID:DTXSID70429027
Nikkaji Number:J751.737H
Wikidata:Q82241910

Synonyms:ethyl(S)-4-benzyloxy-3-hydroxybutyrate;112348-04-6;ETHYL (S)-4-BENZYLOXY-3-HYDROXYBUTYRATE;SCHEMBL7233591;DTXSID70429027;HMHGAAZSPNXMCQ-LBPRGKRZSA-N;(S)-4-(Benzyloxy)-3-hydroxybutyric acid ethyl ester

Suppliers and Price of ethyl(S)-4-benzyloxy-3-hydroxybutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl(S)-4-benzyloxy-3-hydroxybutyrate

Chemical Property:

PSA：55.76000
LogP:1.51730
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:238.12050905
Heavy Atom Count:17
Complexity:212

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(COCC1=CC=CC=C1)O
Isomeric SMILES:CCOC(=O)C[C@@H](COCC1=CC=CC=C1)O

Technology Process of ethyl(S)-4-benzyloxy-3-hydroxybutyrate

There total 9 articles about ethyl(S)-4-benzyloxy-3-hydroxybutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 112348-04-6
ethyl (S)-4-benzyloxy-3-hydroxybutanoate

Guidance literature:

Reference yield: 77.0%

: 100-39-0
benzyl bromide

: 112635-76-4,108585-47-3
(S)-ethyl 3,4-dihydroxybutanoate

: 112348-04-6
ethyl (S)-4-benzyloxy-3-hydroxybutanoate

Guidance literature:: (S)-ethyl 3,4-dihydroxybutanoate; With di(n-butyl)tin oxide; In benzene; at 80 ℃; for 16h;

benzyl bromide; With tetra-(n-butyl)ammonium iodide; In benzene; for 4h; Heating;
DOI:10.1021/jo034930n

Reference yield:

: 60656-87-3
benzyloxyacetoaldehyde

: 112348-04-6
ethyl (S)-4-benzyloxy-3-hydroxybutanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: [Cu{(S,S)-Ph-pybox}][SbF₆]2 / CH₂Cl₂ / 20 h / -40 °C

1.2: KF / acetonitrile / 0.33 h / 20 °C

2.1: 22 percent / K₂CO₃ / 2 h / 20 °C

With potassium carbonate; [Cu{(S,S)-Ph-pybox}][SbF₆]2; In dichloromethane;
DOI:10.1021/ol016096z