1-Ethoxy-1-trimethylsiloxyethene

Base Information

• Chemical Name: 1-Ethoxy-1-trimethylsiloxyethene
• CAS No.: 18295-66-4
• Molecular Formula: C7H16O2Si
• Molecular Weight: 160.288
• DSSTox Substance ID: DTXSID50431123
• Nikkaji Number: J376.944E
• Mol file: 18295-66-4.mol

Synonyms:18295-66-4;1-ethoxy-1-trimethylsiloxyethene;1-ethoxyethenoxy(trimethyl)silane;Silane, [(1-ethoxyethenyl)oxy]trimethyl-;((1-ETHOXYVINYL)OXY)TRIMETHYLSILANE;1-ethoxyvinyloxytrimethylsilane;SCHEMBL1887060;DTXSID50431123;KWKPPZVLRABURT-UHFFFAOYSA-N;1-(Trimethylsiloxy)-1-ethoxyethene;1-ethoxy-1-trimethylsilyloxyethylene;[(1-ethoxyvinyl)oxy](trimethyl)silane;1-(Trimethylsilyloxy)-ethoxyethene ethylacetate-trimethylsilylenol ether;[(1-ETHOXYETHENYL)OXY]TRIMETHYLSILANE

Chemical Property of 1-Ethoxy-1-trimethylsiloxyethene

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 160.091956283
• Heavy Atom Count: 10
• Complexity: 115

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=C)O[Si](C)(C)C

Technology Process of 1-Ethoxy-1-trimethylsiloxyethene

There total 2 articles about 1-Ethoxy-1-trimethylsiloxyethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + ethyl acetate (141-78-6) → trimethylsilanyl-acetic acid ethyl ester (4071-88-9) + 1-ethoxy-1-(trimethylsiloxy)ethene (18295-66-4)

Guidance literature:

ethyl acetate; With lithium diisopropyl amide;

chloro-trimethyl-silane; In tetrahydrofuran; at -78 - -40 ℃; Further stages. Title compound not separated from byproducts.;

DOI:10.1021/jo025944g

Reference yield:

chloro-trimethyl-silane (75-77-4) + fac-(MeCN)(OC)3(Ph3)ReCH2COOEt → (CO)3(P(C6H5)3)ReNCCH3Cl + 1-ethoxy-1-(trimethylsiloxy)ethene (18295-66-4)

Guidance literature:

In not given;

Reference yield: 98.0%

1-ethoxy-1-(trimethylsiloxy)ethene (18295-66-4) + benzaldehyde (100-52-7) → 3-phenyl-3-<(trimethylsilyl)oxy>propanoate d'ethyle (60623-95-2)

Guidance literature:

In toluene; at 23 ℃; for 2h; Inert atmosphere; Molecular sieve;

DOI:10.3987/COM-09-S(S)133

upstream raw materials:

chloro-trimethyl-silane

ethyl acetate

Downstream raw materials:

(S)-5-Benzyloxy-3-hydroxy-4-methyl-pentanoic acid ethyl ester

(3R,4S)-ethyl N,N-dibenzylstatine

(3S,4S)-4-Dibenzylamino-3-hydroxy-6-methyl-heptanoic acid ethyl ester

(3R,4R)-5-Benzyloxy-4-fluoro-3-hydroxy-4-methyl-pentanoic acid ethyl ester