4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole

Base Information

Chemical Name:4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
CAS No.:113264-13-4
Molecular Formula:C10H7ClFNS
Molecular Weight:227.68600
Hs Code.:
DSSTox Substance ID:DTXSID60366558
Wikidata:Q82151826
Mol file:113264-13-4.mol

Synonyms:4-(chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole;113264-13-4;4-(CHLOROMETHYL)-2-(4-FLUOROPHENYL)THIAZOLE;4-(chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole(SALTDATA: FREE);C10H7ClFNS;SCHEMBL201736;DTXSID60366558;HJJPMUWLLCPTRX-UHFFFAOYSA-N;MFCD05273594;STK473447;AKOS000141300;AB21712;4-chloromethyl-2-(4-fluorophenyl)thiazole;4-chloromethyl-2-(4-fluorophenyl) thiazole;EN300-09587;Z56983075

Suppliers and Price of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
250mg
$ 265.00

TRC
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
50mg
$ 65.00

Matrix Scientific
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
500mg
$ 189.00

Crysdot
4-(Chloromethyl)-2-(4-fluorophenyl)thiazole 95+%
1g
$ 301.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
250 mg
$ 115.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
100 mg
$ 58.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
500 mg
$ 200.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
2 g
$ 578.00

Biosynth Carbosynth
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
1 g
$ 340.00

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-2-(4-FLUOROPHENYL)-1,3-THIAZOLE 95.00%
5G
$ 1379.44

Total 5 raw suppliers

Chemical Property of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole

Chemical Property:

PSA：41.13000
LogP:3.68800
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:226.9971763
Heavy Atom Count:14
Complexity:185

Purity/Quality:

97% ^*data from raw suppliers

4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NC(=CS2)CCl)F

Technology Process of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole

There total 6 articles about 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 113264-13-4
4-chloromethyl-2-(4-fluoro phenyl)-thiazole

Guidance literature:: In tetrahydrofuran; ethanol; at 85 ℃; for 10h;

Reference yield: 85.0%

: 22179-72-2
4-fluorothiobenzamide

: 534-07-6
1,3-Dichloroacetone

: 113264-13-4
4-chloromethyl-2-(4-fluoro phenyl)-thiazole

Guidance literature:: In ethanol; at 85 ℃;

Reference yield:

: 132089-35-1
ethyl 2-(4-fluorophenyl)thiazole-4-carboxylate

: 113264-13-4
4-chloromethyl-2-(4-fluoro phenyl)-thiazole

Guidance literature:: ethyl 2-(4-fluorophenyl)thiazole-4-carboxylate; With methanol; sodium tetrahydroborate; In tetrahydrofuran; Reflux;

With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/j.bmc.2021.116133