4'-hydroxy-4-biphenylferrocene

Base Information

• Chemical Name: 4'-hydroxy-4-biphenylferrocene
• CAS No.: 440679-10-7
• Molecular Formula: C₂₂H₁₈FeO
• Molecular Weight: 354.231
• Mol file: 440679-10-7.mol

Synonyms:

Chemical Property of 4'-hydroxy-4-biphenylferrocene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-hydroxy-4-biphenylferrocene

There total 3 articles about 4'-hydroxy-4-biphenylferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

(4-bromophenyl)ferrocene + (p-hydroxyphenyl)boronic acid (71597-85-8) → 4'-hydroxy-4-biphenylferrocene (440679-10-7)

Guidance literature:

With Ba(OH)2; palladium diacetate; In ethanol; arylboronic acid, 4-bromophenylferrocene, Ba(OH)2, and Pd(OAc)2 in 90 % EtOH were shaken for 30 min and stirred for 2 weeks under N2 at r.t.; solvent was removed in vacuo, residue was taken up in CH2Cl2, filtered, washed with water, dried over Na2SO4, solvent was removed in vacuo, residue was chromed. on silica (elution with hexane-CH2Cl2);

DOI:10.1016/S0022-328X(01)01410-3

Reference yield: 24.0%

4'-benzyloxy-4-biphenylferrocene (440679-14-1) + hydrogen (1333-74-0) → 4'-hydroxy-4-biphenylferrocene (440679-10-7)

Guidance literature:

With palladium on charcoal; In tetrahydrofuran; ethanol; ferrocene, 10 % Pd/C in EtOH-THF under H2 were stirred for 76 h and 48 h; react. mixt. was filtered, solvent was removed in vacuo, residue was chromed. on silica;

DOI:10.1016/S0022-328X(01)01410-3

Reference yield:

tris(4-ferrocenylphenyl)boroxine + p-Iodophenol (540-38-5) → 4'-hydroxy-4-biphenylferrocene (440679-10-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In water; N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1016/j.mencom.2015.03.010

upstream raw materials:

(p-hydroxyphenyl)boronic acid

4'-benzyloxy-4-biphenylferrocene

hydrogen

p-Iodophenol