2,2,2-Trifluoro-1-(3-methylphenyl)ethan-1-ol

Base Information

Chemical Name:2,2,2-Trifluoro-1-(3-methylphenyl)ethan-1-ol
CAS No.:1737-23-1
Molecular Formula:C₉H₉F₃O
Molecular Weight:190.165
Hs Code.:
DSSTox Substance ID:DTXSID50505333
Nikkaji Number:J978.889A

Synonyms:1737-23-1;2,2,2-Trifluoro-1-(3-methylphenyl)ethan-1-ol;2,2,2-TRIFLUORO-1-(M-TOLYL)ETHANOL;3-Methyl-alpha-(trifluoromethyl)benzyl Alcohol;SCHEMBL13736755;DTXSID50505333;MTCMVMYGHLVKTA-UHFFFAOYSA-N;BAA73723;MFCD00233112;AKOS010909504;SB84730;SY249791;2,2,2-Trifluoro-1-(m-tolyl)ethan-1-ol;CS-0448385;EN300-90713;Z1603855707

Suppliers and Price of 2,2,2-Trifluoro-1-(3-methylphenyl)ethan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2,2,2-Trifluoro-1-(3-methylphenyl)ethan-1-ol

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:190.06054939
Heavy Atom Count:13
Complexity:167

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC=C1)C(C(F)(F)F)O

Technology Process of 2,2,2-Trifluoro-1-(3-methylphenyl)ethan-1-ol

There total 7 articles about 2,2,2-Trifluoro-1-(3-methylphenyl)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1736-06-7
3'-methyl-2,2,2-trifluoroacetophenone

: 1737-23-1,945732-83-2
1-(3-methylphenyl)-2,2,2-trifluoroethanol

Guidance literature:: With sodium tetrahydroborate; In methanol; water; at 20 ℃; for 5h;
DOI:10.1007/BF00978451

Reference yield: 80.0%

: 407-38-5
2,2,2-trifluoroethyl trifluoroacetate

: 625-95-6
3-Iodotoluene

: 1737-23-1,945732-83-2
1-(3-methylphenyl)-2,2,2-trifluoroethanol

Guidance literature:: 3-Iodotoluene; With TurboGrignard; toluene; In tetrahydrofuran; at -15 ℃; for 0.416667h; Inert atmosphere;

2,2,2-trifluoroethyl trifluoroacetate; In tetrahydrofuran; toluene; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/ejoc.202000550

Reference yield: 72.0%

: 421-53-4
2,2,2-trifluoro-1,1-ethanediol

: 620-23-5
m-tolyl aldehyde

: 1737-23-1,945732-83-2
1-(3-methylphenyl)-2,2,2-trifluoroethanol

Guidance literature:: 2,2,2-trifluoro-1,1-ethanediol; With potassium tert-butylate; In N,N-dimethyl-formamide; at -50 ℃; for 0.583333h;

m-tolyl aldehyde; In N,N-dimethyl-formamide; at -50 ℃; for 1h;
DOI:10.1021/jo400202w