(R)-3-Methoxypyrrolidine

Base Information

Chemical Name:(R)-3-Methoxypyrrolidine
CAS No.:120099-60-7
Molecular Formula:C5H11NO
Molecular Weight:101.148
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50568009
Wikidata:Q72485899
Mol file:120099-60-7.mol

Synonyms:(R)-3-Methoxypyrrolidine;120099-60-7;(3R)-3-methoxypyrrolidine;(R)-3-Methoxy-pyrrolidine;PYRROLIDINE, 3-METHOXY-, (3R)-;MFCD09953439;SCHEMBL492237;SCHEMBL13088406;DTXSID50568009;BWRWNUQAQPAYCK-RXMQYKEDSA-N;AKOS015850978;AM91096;GS-6374;CS-0053757;EN300-147810;P10862;A804430;W-205076

Suppliers and Price of (R)-3-Methoxypyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-3-Methoxypyrrolidine
550mg
$ 165.00

TRC
(R)-3-Methoxypyrrolidine
5g
$ 1320.00

Synthonix
(R)-3-Methoxypyrrolidine 95+%
1g
$ 240.00

Medical Isotopes, Inc.
(R)-3-Methoxypyrrolidine
5 g
$ 2200.00

Matrix Scientific
(3R)-3-Methoxypyrrolidine >95%
5g
$ 1911.00

Matrix Scientific
(3R)-3-Methoxypyrrolidine >95%
1g
$ 738.00

J&W Pharmlab
(R)-3-Methoxy-pyrrolidine 97%
25g
$ 900.00

J&W Pharmlab
(R)-3-Methoxy-pyrrolidine 97%
1g
$ 78.00

J&W Pharmlab
(R)-3-Methoxy-pyrrolidine 97%
5g
$ 250.00

Crysdot
(R)-3-Methoxypyrrolidine 95+%
1g
$ 266.00

Total 25 raw suppliers

Chemical Property of (R)-3-Methoxypyrrolidine

Chemical Property:

Vapor Pressure:13.6mmHg at 25°C
Boiling Point:122.9oC at 760 mmHg
PKA:9.49±0.10(Predicted)
Flash Point:35.2oC
PSA：21.26000
Density:0.94g/cm3
LogP:0.32350
Storage Temp.:2-8°C(protect from light)
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:101.084063974
Heavy Atom Count:7
Complexity:56

Purity/Quality:

97% ^*data from raw suppliers

(R)-3-Methoxypyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1CCNC1
Isomeric SMILES:CO[C@@H]1CCNC1
Uses (R)-3-Methoxypyrrolidine is used in the synthesis of spiroindane based imides as selective MC4R agonists for treating obesity.

Technology Process of (R)-3-Methoxypyrrolidine

There total 4 articles about (R)-3-Methoxypyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 672293-26-4
1-benzyl-3-(R)-methoxy-pyrrolidine

: 120099-60-7
(3R)-3-methoxypyrrolidine

Guidance literature:: With hydrogen; acetic acid; palladium dihydroxide; In ethanol; at 50 ℃; for 3h; under 2068.65 Torr;

Reference yield:

: 549532-08-3
3R-methoxypyrrolidine-1-carboxylic acid tert-butyl ester

: 120099-60-7
(3R)-3-methoxypyrrolidine

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 20 ℃;

Reference yield:

: 74-88-4
methyl iodide

: 120099-60-7
(3R)-3-methoxypyrrolidine

: 549532-08-3
3R-methoxypyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: (R)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate; With sodium hydride; at 20 ℃; for 0.166667h;

methyl iodide; for 48h;