C₁₈H₁₇NO₅

Base Information

• Chemical Name: C₁₈H₁₇NO₅
• CAS No.: 1173933-71-5
• Molecular Formula: C₁₈H₁₇NO₅
• Molecular Weight: 327.337
• Mol file: 1173933-71-5.mol

Synonyms:

Chemical Property of C₁₈H₁₇NO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₁₇NO₅

There total 3 articles about C₁₈H₁₇NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formic acid (64-18-6) + C17H17NO4 (1173933-70-4) → C18H17NO5 (1173933-71-5)

Guidance literature:

formic acid; C₁₇H₁₇NO₄; With sodium formate; acetic anhydride; at 20 ℃; for 4h;

With hydrogenchloride; In methanol; water; at 20 ℃; for 24h;

DOI:10.1016/j.ejmech.2010.11.025

Reference yield:

L-DOPA methyl ester (7101-51-1) → C18H17NO5 (1173933-71-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate; acetic acid / 20 h / 20 °C

2: sodium formate; acetic anhydride / 4 h / 20 °C

With sodium formate; sodium acetate; acetic anhydride; acetic acid; 1: |Pictet-Spengler Synthesis;

DOI:10.1016/j.cclet.2013.02.014

Reference yield:

levodopa (59-92-7,90638-38-3) → C18H17NO5 (1173933-71-5)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / 72 h / 20 °C

2: sodium acetate; acetic acid / 20 h / 20 °C

3: sodium formate; acetic anhydride / 4 h / 20 °C

With thionyl chloride; sodium formate; sodium acetate; acetic anhydride; acetic acid; 2: |Pictet-Spengler Synthesis;

DOI:10.1016/j.cclet.2013.02.014

upstream raw materials:

formic acid

C₁₇H₁₇NO₄

levodopa

L-DOPA methyl ester

Downstream raw materials:

C₂₀H₂₁NO₅

C₅₂H₇₀N₄O₈

C₅₃H₇₂N₄O₈

C₅₄H₇₄N₄O₈

Refernces

• 1、 Xu, Geng,Yan, Zheng,Wang, Nan,Liu, Zhanzhu. "Synthesis and cytotoxicity of cis-dichloroplatinum (II) complexes of (1S,3S)-1,2,3,4-tetrahydroisoquinolines". scheme or table. p. 356 - 363. Retrieved 2011/02/26.