N-(2,4-difluorophenyl)-2,2,2-trifluoroacetamide

Base Information

Chemical Name:N-(2,4-difluorophenyl)-2,2,2-trifluoroacetamide
CAS No.:98651-71-9
Molecular Formula:C₈H₄F₅NO
Molecular Weight:225.118
Hs Code.:
European Community (EC) Number:825-953-7
DSSTox Substance ID:DTXSID801243695

Synonyms:N-(2,4-difluorophenyl)-2,2,2-trifluoroacetamide;98651-71-9;starbld0010309;SCHEMBL9359721;DTXSID801243695;trifluoroacetyl-2,4-difluoroaniline;MFCD00751600;AKOS003847286;CT-0052;CS-0253597;EN300-6474646

Suppliers and Price of N-(2,4-difluorophenyl)-2,2,2-trifluoroacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N-(2,4-difluorophenyl)-2,2,2-trifluoroacetamide

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:225.02130456
Heavy Atom Count:15
Complexity:242

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)F)NC(=O)C(F)(F)F

Technology Process of N-(2,4-difluorophenyl)-2,2,2-trifluoroacetamide

There total 3 articles about N-(2,4-difluorophenyl)-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 367-25-9,76563-56-9
2,4-difluorophenylamine

: 407-25-0
trifluoroacetic anhydride

: 98651-71-9
N-(2,4-Difluorophenyl)-trifluoroacetamide

Guidance literature:: for 0.0833333h; Heating;

Reference yield:

: 404-24-0
2,2,2-trifluoro-N-phenylacetamide

: 35980-25-7
N-(4-fluorophenyl)-2,2,2-trifluoro-acetamide

: 98651-71-9
N-(2,4-Difluorophenyl)-trifluoroacetamide

: 98634-00-5
N-(2,6-difluorophenyl)-2,2,2-trifluoroacetamide

: 61984-68-7
2,2,2-trifluoro-N-(2-fluorophenyl)acetamide

Guidance literature:: With hypofluorous acid trifluoromethyl ester; In trifluoroacetic acid;
DOI:10.1021/jo00223a030

Reference yield:

: 83164-33-4
N-(2,4-difluorophenyl)-2-(3-trifluoromethylphenoxy)-3-pyridinecarboxamide

: 98651-71-9
N-(2,4-Difluorophenyl)-trifluoroacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: HCl, AcOH / H₂O / 48 h / Heating

2: 94 percent / 0.08 h / Heating

With hydrogenchloride; acetic acid; In water;