Technology Process of di-tert-butyldimethylsilyl-2-aminoresorcinol
There total 2 articles about di-tert-butyldimethylsilyl-2-aminoresorcinol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen / PtO2 / ethanol / 2068.6 Torr
2: imidazole / dimethylformamide / Ambient temperature
With
1H-imidazole; hydrogen;
platinum(IV) oxide;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1139/v81-432
- Guidance literature:
-
With
1H-imidazole;
In
N,N-dimethyl-formamide;
Yield given;
Ambient temperature;
DOI:10.1139/v81-432
- Guidance literature:
-
Multi-step reaction with 8 steps
1: p-TsOH / benzene / Heating
2: CH2Cl2 / 1 h / -20 °C
3: 1) ozone; 2) NaBH4 / 1) EtOH, CH2Cl2, -78 deg C; 2) -40 deg C --> room temp.
4: 95 percent / Et3N / CH2Cl2 / 1) -78 deg C, O.5 h; 2) room temp., 1 h
5: 95 percent / KF / 18-crown-6 / acetonitrile
6: 85 percent / Et3N / CH2Cl2 / 1) 0 deg C 10 min; 2) 1 h, room temp.
7: 86 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
8: 52 percent / n-Bu4NF / tetrahydrofuran / 0.17 h
With
potassium fluoride; sodium tetrahydroborate; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; ozone; triethylamine;
18-crown-6 ether;
In
tetrahydrofuran; dichloromethane; acetonitrile; benzene;
DOI:10.1139/v81-432
