Methyl 2-methylpyrrolidine-2-carboxylate

Base Information

Chemical Name:Methyl 2-methylpyrrolidine-2-carboxylate
CAS No.:51098-47-6
Molecular Formula:C₇H₁₃NO₂
Molecular Weight:143.186
Hs Code.:
European Community (EC) Number:820-185-9

Synonyms:METHYL 2-METHYLPYRROLIDINE-2-CARBOXYLATE;51098-47-6;2-methyl-pyrrolidine-2-carboxylic acid methyl ester;SCHEMBL2972762;CCNBDZFBJCGDIV-UHFFFAOYSA-N;AKOS006348945;AB76260;methyl 2-methyl-2-pyrrolidinecarboxylate;EN300-153625;METHYL2-METHYLPYRROLIDINE-2-CARBOXYLATE

Suppliers and Price of Methyl 2-methylpyrrolidine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
methyl2-methylpyrrolidine-2-carboxylate
250mg
$ 350.00

TRC
methyl2-methylpyrrolidine-2-carboxylate
50mg
$ 90.00

Total 3 raw suppliers

Chemical Property of Methyl 2-methylpyrrolidine-2-carboxylate

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:143.094628657
Heavy Atom Count:10
Complexity:147

Purity/Quality:

97% ^*data from raw suppliers

methyl2-methylpyrrolidine-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(CCCN1)C(=O)OC

Technology Process of Methyl 2-methylpyrrolidine-2-carboxylate

There total 5 articles about Methyl 2-methylpyrrolidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 141870-95-3
(+/-)-1-benzyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate

: 51098-47-6
methyl-2-methyl-pyrrolidine-2-carboxylate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 25 ℃; for 5h;

Reference yield:

: 108645-62-1
N-benzyloxycarbonylproline methyl ester

: 51098-47-6
methyl-2-methyl-pyrrolidine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 4 h / -78 °C

1.2: 25 °C

2.1: hydrogen / palladium 10% on activated carbon / methanol / 5 h / 25 °C

With hydrogen; lithium diisopropyl amide; palladium 10% on activated carbon; In tetrahydrofuran; methanol;

Reference yield:

: 63427-91-8
1-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid

: 51098-47-6
methyl-2-methyl-pyrrolidine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C

2.1: palladium 10% on activated carbon; hydrogen / methanol

With palladium 10% on activated carbon; hydrogen; lithium hexamethyldisilazane; In tetrahydrofuran; methanol;