2-Fluoro-1-nitro-4-(trifluoromethoxy)benzene

Base Information

• Chemical Name: 2-Fluoro-1-nitro-4-(trifluoromethoxy)benzene
• CAS No.: 123572-64-5
• Molecular Formula: C7H3F4NO3
• Molecular Weight: 225.099
• Hs Code.: 2909309090
• Mol file: 123572-64-5.mol

Synonyms:2-Fluoro-1-methylenecyclopropane;2-fluoro-1-nitro-4-trifluoromethoxy-benzene;Cyclopropane,1-fluoro-2-methylene;

Chemical Property of 2-Fluoro-1-nitro-4-(trifluoromethoxy)benzene

Chemical Property:

• PSA: 55.05000
• LogP: 3.15570

Purity/Quality:

98% ^*data from raw suppliers

2-Fluoro-1-nitro-4-(trifluoromethoxy)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Fluoro-1-nitro-4-(trifluoromethoxy)benzene

There total 2 articles about 2-Fluoro-1-nitro-4-(trifluoromethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

meta-fluoro(trifluoromethoxy)benzene (1077-01-6) → 2-fluoro-1-nitro-4-(trifluoromethoxy) benzene (123572-64-5)

Guidance literature:

With sulfuric acid; potassium nitrate; at 0 ℃; for 1h;

Reference yield:

meta-fluoro(trifluoromethoxy)benzene (1077-01-6) → 4-fluoro-1-nitro-2-(trifluoromethoxy)benzene (123572-65-6) + 2-fluoro-1-nitro-4-(trifluoromethoxy) benzene (123572-64-5)

Guidance literature:

With sulfuric acid; nitric acid; at 0 - 20 ℃;

Reference yield: 69.0%

2-fluoro-1-nitro-4-(trifluoromethoxy) benzene (123572-64-5) + Cyclopropylamine (765-30-0) → N-cyclopropyl-2-nitro-5-(trifluoromethoxy)aniline

Guidance literature:

With potassium carbonate; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;

upstream raw materials:

meta-fluoro(trifluoromethoxy)benzene

Downstream raw materials:

4-methyl-1-(2-nitro-5-trifluoromethoxy-phenyl)-1H-imidazole

2-fluoro-4-(trifluoromethoxy)aniline

1-bromo-2-fluoro-4-(trifluoromethoxy)benzene

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