ethyl bis(2-hydroxy-4-methylphenyl)phosphinate

Base Information

• Chemical Name: ethyl bis(2-hydroxy-4-methylphenyl)phosphinate
• CAS No.: 99706-40-8
• Molecular Formula: C₁₆H₁₉O₄P
• Molecular Weight: 306.298
• Mol file: 99706-40-8.mol

Synonyms:

Chemical Property of ethyl bis(2-hydroxy-4-methylphenyl)phosphinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl bis(2-hydroxy-4-methylphenyl)phosphinate

There total 1 articles about ethyl bis(2-hydroxy-4-methylphenyl)phosphinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl bis(3-methylphenyl) phosphate (99706-37-3) → ethyl bis(2-hydroxy-4-methylphenyl)phosphinate (99706-40-8)

Guidance literature:

With n-butyllithium; diisopropylamine; Yield given. Multistep reaction; 1.) THF, -78 deg C, 1 h, b) RT, 3 h;

DOI:10.1021/jo00352a010

Reference yield:

ethyl bis(2-hydroxy-4-methylphenyl)phosphinate (99706-40-8) → bis(2-hydroxy-4-methylphenyl)phosphinic acid (99706-44-2)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium iodide / acetonitrile / 24 h / Ambient temperature

2: water

With water; sodium iodide; In acetonitrile;

DOI:10.1021/jo00352a010

Reference yield:

chloro-trimethyl-silane (75-77-4) + ethyl bis(2-hydroxy-4-methylphenyl)phosphinate (99706-40-8) → C17H23O4PSi

Guidance literature:

With sodium iodide; In acetonitrile; for 24h; Ambient temperature;

DOI:10.1021/jo00352a010

upstream raw materials:

ethyl bis(3-methylphenyl) phosphate

Downstream raw materials:

bis(2-hydroxy-4-methylphenyl)phosphinic acid