(2S)-1-aMino-2-PyrrolidineMethanol

Base Information

Chemical Name:(2S)-1-aMino-2-PyrrolidineMethanol
CAS No.:127221-89-0
Molecular Formula:C5H12N2O
Molecular Weight:116.163
Hs Code.:
Mol file:127221-89-0.mol

Synonyms:1-aminoprolinol;(S)-1-amino-2-hydroxymethylpyrrolidine;((S)-1-Amino-pyrrolidin-2-yl)-methanol;(S)-(-)-1-amino-2-(hydroxymethyl)pyrrolidine;(2S)-1-amino-2-Pyrrolidinemethanol;(S)-1-amino-2-(hydroxymethyl)pyrrolidine;(S)-(1-Aminopyrrolidin-2-yl)methanol;(2S)-1-amiino-2-PyrrolidineMethanol;1-amino-2-(S)-hydroxymethylpyrrolidine;

Suppliers and Price of (2S)-1-aMino-2-PyrrolidineMethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-(1-Aminopyrrolidin-2-yl)methanol 95+%
1g
$ 1250.00

Chemenu
(S)-(1-Aminopyrrolidin-2-yl)methanol 95%
1g
$ 1178.00

Alichem
(S)-(1-Aminopyrrolidin-2-yl)methanol
1g
$ 1310.40

AccelPharmtech
(2S)-1-amino-2-Pyrrolidinemethanol 90.0%
5G
$ 1080.00

AccelPharmtech
(2S)-1-amino-2-Pyrrolidinemethanol 90.0%
1G
$ 360.00

Total 6 raw suppliers

Chemical Property of (2S)-1-aMino-2-PyrrolidineMethanol

Chemical Property:

Boiling Point:92 - 96 °C (3 mmHg)
PKA:14.77±0.10(Predicted)
PSA：49.49000
Density:1.096±0.06 g/cm3(Predicted)
LogP:-0.04500

Purity/Quality:

97% ^*data from raw suppliers

(S)-(1-Aminopyrrolidin-2-yl)methanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S)-1-aMino-2-PyrrolidineMethanol

There total 4 articles about (2S)-1-aMino-2-PyrrolidineMethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 58246-54-1
1-Nitroso-2(S)-pyrrolidinemethanol

: 127221-89-0
(S)-(-)-1-amino-2-(hydroxymethyl)pyrrolidine

Guidance literature:: 1-Nitroso-2(S)-pyrrolidinemethanol; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; Inert atmosphere; Reflux;

In tetrahydrofuran; at 0 ℃; Reflux; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.04.042

Reference yield:

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

: 127221-89-0
(S)-(-)-1-amino-2-(hydroxymethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium nitrite; silica sulfuric acid

2: LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; sulfuric acid; silica gel; sodium nitrite; In tetrahydrofuran;
DOI:10.1016/j.tetasy.2005.09.027

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 127221-89-0
(S)-(-)-1-amino-2-(hydroxymethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 3 steps

1: 66 percent / LiAlH₄ / tetrahydrofuran / 6 h / Heating

2: 91 percent / NaNO₂, glacial acetic acid / H₂O / 5 h / Ambient temperature

3: LiAlH₄ / tetrahydrofuran / 3 h / Heating

With lithium aluminium tetrahydride; acetic acid; sodium nitrite; In tetrahydrofuran; water;