Butanoyl chloride, 4-(dimethylamino)-

Base Information

• Chemical Name: Butanoyl chloride, 4-(dimethylamino)-
• CAS No.: 127527-22-4
• Molecular Formula: C6H12ClNO
• Molecular Weight: 149.62
• Mol file: 127527-22-4.mol

Synonyms:4-(dimethylamino)butanoyl chloride;4-dimethylamino-butyrylchloride;4-dimethylaminobutyric acid chloride;4-dimethylamino-butyryl chloride;4-(N,N-dimethylamino)butyrylchloride;4-dimethylamonobutanoyl chloride;

Chemical Property of Butanoyl chloride, 4-(dimethylamino)-

Chemical Property:

• PSA: 20.31000
• LogP: 1.09360

Purity/Quality:

4-(Dimethylamino)butanoylchloridehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Butanoyl chloride, 4-(dimethylamino)-

There total 4 articles about Butanoyl chloride, 4-(dimethylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine (383865-57-4) → 4-Dimethylamino-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-butyramide + 4-(N,N-dimethylamino)butanoyl chloride (127527-22-4)

Guidance literature:

Reference yield:

4-dimethylamino-butyric acid (693-11-8) → 4-(N,N-dimethylamino)butanoyl chloride (127527-22-4)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; at 30 - 35 ℃; for 2h; Inert atmosphere;

DOI:10.1021/jm4004076

Reference yield:

4-(dimethylamino)butyric acid hydrochloride (69954-66-1) → 4-(N,N-dimethylamino)butanoyl chloride (127527-22-4)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; Inert atmosphere;

upstream raw materials:

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine

oxalyl dichloride

testosterone

4-(dimethylamino)butyric acid hydrochloride

Downstream raw materials:

C₃₃H₄₁F₃N₈O₃

N-(4-((3-chloro-4-fluorophenyl)amino)thieno[2,3-d]pyrimidin-6-yl)-4-(dimethylamino)butanamide

C₅₃H₅₆N₁₄O₈S₆

4-dimethylaminobutanoic acid [4-(5-chloro-4-fluoro-3-methylphenylamino)-3-methyl-7-methoxyquinolin-6-yl]amide hydrochloride