Benzene, [[(1E)-2-fluoro-1-propyl-1-pentenyl]seleno]-

Base Information

• Chemical Name: Benzene, [[(1E)-2-fluoro-1-propyl-1-pentenyl]seleno]-
• CAS No.: 129053-33-4
• Molecular Formula: C14H19FSe
• Molecular Weight: 285.263
• Mol file: 129053-33-4.mol

Synonyms:

Chemical Property of Benzene, [[(1E)-2-fluoro-1-propyl-1-pentenyl]seleno]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, [[(1E)-2-fluoro-1-propyl-1-pentenyl]seleno]-

There total 20 articles about Benzene, [[(1E)-2-fluoro-1-propyl-1-pentenyl]seleno]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

xenon difluoride (13709-36-9) + 4-Octyne (1942-45-6) + trimethylstannyl phenyl selenide (4848-71-9) → (E)-4-fluoro-5-(phenylseleno)oct-4-ene (129053-33-4) + trimethyltin fluoride (420-60-0)

Guidance literature:

In dichloromethane; XeF2 added in small portions under Ar to a soln. of selenide in CH2Cl2 at -20°C, stirred for 30 min, the acetylene added, stirred for 1 h at -20°C and for 1 h at room temp.; precipitate separated, washed with n-pentane, solvent removed under vacuum, crude product purified by column chromy., elem. anal.;

DOI:10.1002/(SICI)1099-0682(200006)2000:6<1307::AID-EJIC1307>3.3.CO;2-Q

Reference yield: 86.0%

N-phenylselanylphthalimide (71098-88-9) + 4-Octyne (1942-45-6) → (E)-4-fluoro-5-(phenylseleno)oct-4-ene (129053-33-4)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In dichloromethane; at 25 ℃; for 46h;

DOI:10.1016/0040-4039(90)80089-5

Reference yield: 78.0%

4-Octyne (1942-45-6) + diphenyl diselenide (1666-13-3) → (E)-4-fluoro-5-(phenylseleno)oct-4-ene (129053-33-4)

Guidance literature:

With p-iodotoluene difluoride; In dichloromethane; at 25 ℃; for 2h;

DOI:10.1055/s-2004-832827

upstream raw materials:

N-phenylselanylphthalimide

4-Octyne

benzeneselenyl fluoride

phenyl trimethylsilyl selenide

Downstream raw materials:

C₁₄H₁₉FOSe