2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide

Base Information

• Chemical Name: 2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide
• CAS No.: 129378-52-5
• Molecular Formula: C11H23N3O2SSi
• Molecular Weight: 289.474
• European Community (EC) Number: 834-837-5
• Nikkaji Number: J1.542.384F
• Mol file: 129378-52-5.mol

Synonyms:129378-52-5;2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide;N,N-Dimethyl-2-(tert-butyldimethylsilanyl)imidazole-1-sulfonamide;2-[tert-butyl(dimethyl)silyl]-N,N-dimethylimidazole-1-sulfonamide;C11H23N3O2SSi;SCHEMBL226223;MFCD12963638;2-[(1,1-Dimethylethyl)dimethylsilyl]-N,N-dimethyl-1H-imidazole-1sulfonamide;BS-15157;B5658;CS-0088540;T70193;EN300-18780454;1-Dimethylsulfamoyl-2-t-butyldimethylsilyl imidazole;1-N-(dimethylsulfamoyl)-2-tert-butyldimethylsilyl imidazole;1- N-(dimethylsulfamoyl)-2-tert-butyldimethylsilyl imidazole;1-(Dimethylsulfamoyl)-2-(tert-butyldimethylsilyl)-1H-imidazole;1-(N,N-dimethylsulphamoyl)-2-tert-butyldimethylsilylimidazole;2-(tert-butyldimethylsilyl)-1-(N,N-dimethylsulfamoyl) imidazole;N,N-Dimethyl-2-(tert-butyldimethylsilyl)-1H-imidazole-1-sulfonamide;2-(tert-butyl-dimethyl-silanyl)-imidazole-1-sulfonic acid dimethylamide;2-[tert-butyl(dimethyl)silyl]-n,n-dimethyl-1h-imidazole-1-sulphonamide

Chemical Property of 2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide

Chemical Property:

• Vapor Pressure: 3.07E-05mmHg at 25°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 289.12802469
• Heavy Atom Count: 18
• Complexity: 396

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)C1=NC=CN1S(=O)(=O)N(C)C

Technology Process of 2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide

There total 9 articles about 2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N,N-dimethyl-1H-imidazole-1-sulfonamide (78162-58-0) + tert-butyldimethylsilyl chloride (18162-48-6) → 2-tert-butyldimethylsilyl-N,N-dimethylimidazole-1-sulfonamide (129378-52-5)

Guidance literature:

N,N-dimethyl-1H-imidazole-1-sulfonamide; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; at 20 ℃; for 24h;

Reference yield:

cyclohexanedione monoethylene ketal (4746-97-8) + trimethyl phosphonoacetate (5927-18-4) → 2-tert-butyldimethylsilyl-N,N-dimethylimidazole-1-sulfonamide (129378-52-5)

Guidance literature:

With NaH; In tetrahydrofuran; diethyl ether;

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + N,N-dimethyl-1H-imidazole-1-sulfonamide (78162-58-0) + tert-butyldimethylsilyl chloride (18162-48-6) → 2-tert-butyldimethylsilyl-N,N-dimethylimidazole-1-sulfonamide (129378-52-5)

Guidance literature:

With ammonium chloride; In tetrahydrofuran; diethyl ether;

upstream raw materials:

1-chloro 4-iodobutane

N,N-dimethyl-1H-imidazole-1-sulfonamide

tert-butyldimethylsilyl chloride

1-iodo-3-chloro-propane

Downstream raw materials:

2-(t-butyldimethylsilyl)-5-hydroxydiphenylmethyl-N,N-dimethylimidazole-1-sulphonamide

N,N-dimethyl-1H-imidazole-1-sulfonamide

2-(tert-butyldimethylsilyl)-5-(2-deoxy-3,5-di-O-benzyl-D-ribosyl)-N,N-dimethylimidazole-1-sulfonamide

2-(tert-butyldimethylsilyl)-5-(2-deoxy-3,5-di-O-benzyl-D-ribosyl)-N,N-dimethylimidazole-1-sulfonamide