neryl p-tolyl sulfone

Base Information

• Chemical Name: neryl p-tolyl sulfone
• CAS No.: 68690-44-8
• Molecular Formula: C₁₇H₂₄O₂S
• Molecular Weight: 292.442
• Mol file: 68690-44-8.mol

Synonyms:

Chemical Property of neryl p-tolyl sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of neryl p-tolyl sulfone

There total 6 articles about neryl p-tolyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(Z)-neryl bromide (25996-10-5) + sodium 4-methylbenzenesulfinate (824-79-3) → neryl p-tolyl sulfone (68690-44-8)

Guidance literature:

In N,N-dimethyl-formamide; for 24h; Ambient temperature;

DOI:10.1055/s-1984-31007

Reference yield: 14.0%

neryl acetate (141-12-8,8022-83-1) + sodium 4-methylbenzenesulfinate (824-79-3) → 3,7-dimethyl-3-(p-tolylsulfonyl)-1,6-octadiene (72863-23-1) + neryl p-tolyl sulfone (68690-44-8) + 3,7-dimethyl-1-(p-toluenesulfonyl)-2(E),6-octadiene (53254-60-7) + 1-[2-Eth-(E)-ylidene-6-methyl-hept-5-ene-1-sulfonyl]-4-methyl-benzene + 1-Methyl-4-(7-methyl-3-methylene-oct-6-ene-2-sulfonyl)-benzene

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 19 ℃; for 65h; Product distribution; other acetates, other reagents;

DOI:10.1016/S0022-328X(00)85727-7

Reference yield:

Nerol (106-25-2) → neryl p-tolyl sulfone (68690-44-8)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₃ / diethyl ether / 0.17 h / 0 °C

2: 93 percent / dimethylformamide / 24 h / Ambient temperature

With phosphorus tribromide; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1055/s-1984-31007

upstream raw materials:

neryl acetate

sodium 4-methylbenzenesulfinate

(Z)-neryl bromide

3,7-dimethyl-3-(p-tolylsulfonyl)-1,6-octadiene

Downstream raw materials:

4,8-Dimethyl-2-p-tolylsulfonyl-3(Z),7-nonadienoic acid

1-Methyl-4-((5Z,9Z)-6,10,14-trimethyl-pentadeca-5,9,13-trien-1-yne-8-sulfonyl)-benzene

1-((6Z,10Z,14Z)-16-Benzyloxy-2,6,10,14-tetramethyl-hexadeca-2,6,10,14-tetraene-8-sulfonyl)-4-methyl-benzene

1-[(1S,2R,3R)-2-((E)-2,6-Dimethyl-hepta-1,5-dienyl)-3-(1,5-dimethyl-hex-4-enyl)-cyclopropanesulfonyl]-4-methyl-benzene