Methyl 5-(hydroxymethyl)nicotinate

Base Information

Chemical Name:Methyl 5-(hydroxymethyl)nicotinate
CAS No.:129747-52-0
Molecular Formula:C8H9NO3
Molecular Weight:167.164
Hs Code.:2933399090
European Community (EC) Number:884-472-0
DSSTox Substance ID:DTXSID30570943
Wikidata:Q82458519
Mol file:129747-52-0.mol

Synonyms:Methyl 5-(hydroxymethyl)nicotinate;129747-52-0;Methyl 5-(hydroxymethyl)pyridine-3-carboxylate;5-HYDROXYMETHYL-NICOTINIC ACID METHYL ESTER;3-Pyridinecarboxylic acid, 5-(hydroxymethyl)-, methyl ester;5-(Hydroxymethyl)-3-pyridinecarboxylic Acid Methyl Ester;MFCD11848097;methyl 5-hydroxymethylnicotinate;SCHEMBL2008389;DTXSID30570943;UXSXEOUOALNTGR-UHFFFAOYSA-N;Methyl (5-hydroxymethyl)nicotinate;AMY14067;AKOS016007423;5-Hydroxymethyl-nicotinicacidmethylester;CS-W019713;SB10953;DS-15449;SY113504;EN300-704146;J-517614;Z1255439543

Suppliers and Price of Methyl 5-(hydroxymethyl)nicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(Hydroxymethyl)-3-pyridinecarboxylicAcidMethylEster
25mg
$ 770.00

Medical Isotopes, Inc.
5-(Hydroxymethyl)-3-pyridinecarboxylicAcidMethylEster
100 mg
$ 3750.00

Labseeker
5-Hydroxymethyl-nicotinicacidmethylester 95
5g
$ 1633.00

J&W Pharmlab
5-Hydroxymethyl-nicotinicacidmethylester 96%
5g
$ 1750.00

J&W Pharmlab
5-Hydroxymethyl-nicotinicacidmethylester 96%
1g
$ 498.00

Crysdot
Methyl5-(hydroxymethyl)nicotinate 97%
10g
$ 774.00

Crysdot
Methyl5-(hydroxymethyl)nicotinate 97%
25g
$ 1555.00

Crysdot
Methyl5-(hydroxymethyl)nicotinate 97%
5g
$ 462.00

Chemenu
Methyl5-(hydroxymethyl)nicotinate 97%
5g
$ 437.00

Chemenu
Methyl5-(hydroxymethyl)nicotinate 97%
1g
$ 158.00

Total 23 raw suppliers

Chemical Property of Methyl 5-(hydroxymethyl)nicotinate

Chemical Property:

Boiling Point:316.3±32.0 °C(Predicted)
PKA:13.40±0.10(Predicted)
PSA：59.42000
Density:1.244±0.06 g/cm3(Predicted)
LogP:0.36050
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:167.058243149
Heavy Atom Count:12
Complexity:160

Purity/Quality:

99%, ^*data from raw suppliers

5-(Hydroxymethyl)-3-pyridinecarboxylicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CN=CC(=C1)CO
Uses 5-(Hydroxymethyl)-3-pyridinecarboxylic Acid Methyl Ester is an intermediate in the synthesis of Nornicotine (N757000) analogs to be used as haptens for immunoassays.

Technology Process of Methyl 5-(hydroxymethyl)nicotinate

There total 10 articles about Methyl 5-(hydroxymethyl)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 179072-13-0
5-(tert-Butyl-diphenyl-silanyloxymethyl)-nicotinic acid methyl ester

: 129747-52-0
methyl 5-(hydroxymethyl)pyridine-3-carboxylate

Guidance literature:: With ammonium fluoride; In methanol; at 60 ℃; for 3h;
DOI:10.1080/07328319608007388

Reference yield: 75.0%

: 67-56-1
methanol

: 37669-64-0
(5-bromopyridin-3-yl)methanol

: 201230-82-2
carbon monoxide

: 129747-52-0
methyl 5-(hydroxymethyl)pyridine-3-carboxylate

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine; at 80 ℃; for 16h; under 15201 Torr;

Reference yield:

: 25761-06-2
5-methoxycarbonylpyrid-3-ylcarbonylchloride

: 129747-52-0
methyl 5-(hydroxymethyl)pyridine-3-carboxylate

Guidance literature:: 5-methoxycarbonylpyrid-3-ylcarbonylchloride; With lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; at -78 - 20 ℃; for 16h;

With hydrogenchloride; In tetrahydrofuran; water;