4-(Phenylsulfanyl)-2,3-dihydrofuran

Base Information

Chemical Name:4-(Phenylsulfanyl)-2,3-dihydrofuran
CAS No.:130307-35-6
Molecular Formula:C10H10OS
Molecular Weight:178.255
Hs Code.:
DSSTox Substance ID:DTXSID40563720
Wikidata:Q82448198

Synonyms:130307-35-6;4-(Phenylthio)-2,3-dihydrofuran;4-(Phenylsulfanyl)-2,3-dihydrofuran;DTXSID40563720;4,5-DIHYDRO-3-FURANYL PHENYL SULFIDE

Suppliers and Price of 4-(Phenylsulfanyl)-2,3-dihydrofuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(Phenylsulfanyl)-2,3-dihydrofuran

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:178.04523611
Heavy Atom Count:12
Complexity:171

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC=C1SC2=CC=CC=C2

Technology Process of 4-(Phenylsulfanyl)-2,3-dihydrofuran

There total 6 articles about 4-(Phenylsulfanyl)-2,3-dihydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1191-99-7,75454-45-4
2,3-dihydro-2H-furan

: 931-59-9
benzenesulfenyl chloride

: 130307-35-6
3-(phenylthio)-4,5-dihydrofuran

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -70 - 20 ℃; for 1h;
DOI:10.1021/jo030256y

Reference yield: 65.0%

: 1191-99-7,75454-45-4
2,3-dihydro-2H-furan

: 1193-82-4
racemic methyl phenyl sulfoxide

: 130307-35-6
3-(phenylthio)-4,5-dihydrofuran

Guidance literature:: racemic methyl phenyl sulfoxide; With trifluoroacetic anhydride; In dichloromethane; at -78 ℃; for 0.25h;

2,3-dihydro-2H-furan; In dichloromethane; at -78 ℃; for 0.25h;

With triethylamine; In dichloromethane; at -78 - 20 ℃; Further stages.;
DOI:10.1002/1521-3765(20010917)7:18<3890::AID-CHEM3890>3.0.CO;2-Y

Reference yield:

: 108-95-2,27073-41-2
phenol

: 130307-35-6
3-(phenylthio)-4,5-dihydrofuran

Guidance literature:: Multi-step reaction with 2 steps

1: N-chlorosuccinimide / CH₂Cl₂ / 0.5 h / 0 °C

2: 71 percent / KOBu-t / tetrahydrofuran / 1 h / -70 - 20 °C

With N-chloro-succinimide; potassium tert-butylate; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo030256y