4-fluorophenylbutyric acid

Base Information

Chemical Name:4-fluorophenylbutyric acid
CAS No.:7139-24-4
Molecular Formula:C₁₀H₁₁FO₂
Molecular Weight:182.195
Hs Code.:

Synonyms:

Suppliers and Price of 4-fluorophenylbutyric acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-fluorophenylbutyric acid

Chemical Property:

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Technology Process of 4-fluorophenylbutyric acid

There total 6 articles about 4-fluorophenylbutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 124-38-9,18923-20-1
carbon dioxide

: 699-01-4
1-fluoro-4-(prop-1-en-1-yl)benzene

: 7139-24-4,90794-16-4
4-fluorophenylbutyric acid

Guidance literature:: 1-fluoro-4-(prop-1-en-1-yl)benzene; With 9-borabicyclo[3.3.1]nonane dimer; In 1,2-dimethoxyethane; at 70 ℃; for 24h; Glovebox;

carbon dioxide; With cesium fluoride; In 1,2-dimethoxyethane; at 120 ℃; for 24h; regioselective reaction; Glovebox;
DOI:10.1039/c9sc02467k

Reference yield:

: 74-96-4
ethyl bromide

: 405-50-5
p-Fluorophenylacetic acid

: 7139-24-4,90794-16-4
4-fluorophenylbutyric acid

Guidance literature:: p-Fluorophenylacetic acid; With n-butyllithium; In tetrahydrofuran; hexanes; at -78 - 25 ℃;

ethyl bromide; In tetrahydrofuran; hexanes; at 20 - 25 ℃; for 16h;
DOI:10.1002/adsc.200900538

Reference yield:

: 75-03-6
ethyl iodide

: 405-50-5
p-Fluorophenylacetic acid

: 7139-24-4,90794-16-4
4-fluorophenylbutyric acid

Guidance literature:: p-Fluorophenylacetic acid; With n-butyllithium; In tetrahydrofuran; hexanes; at 0 ℃; for 0.166667h; Inert atmosphere;

ethyl iodide; In tetrahydrofuran; hexanes; Inert atmosphere;
DOI:10.1021/ja205107x