trans-2-p-Chlorphenyl-3-methyl-oxiran

Base Information

• Chemical Name: trans-2-p-Chlorphenyl-3-methyl-oxiran
• CAS No.: 885318-84-3
• Molecular Formula: C₉H₉ClO
• Molecular Weight: 168.623
• Mol file: 885318-84-3.mol

Synonyms:

Chemical Property of trans-2-p-Chlorphenyl-3-methyl-oxiran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2-p-Chlorphenyl-3-methyl-oxiran

There total 3 articles about trans-2-p-Chlorphenyl-3-methyl-oxiran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

E-1-(4-chlorophenyl)-1-propene (1879-53-4) → trans-2-p-Chlorphenyl-3-methyl-oxiran (885318-84-3)

Guidance literature:

With E_. coli JM₁₀₉ (pTAB₁₉); In 2,2,4-trimethylpentane; at 30 ℃;

DOI:10.1016/j.tetasy.2006.01.009

Reference yield:

cis-1-phenyl-1-propylene (766-90-5) → trans-2-p-Chlorphenyl-3-methyl-oxiran (885318-84-3) + cis-4-chloro-β-methylstyrene oxide (135682-94-9) + cis-4-chloro-β-methylstyrene oxide + (2R,3R)-2-(4-Chloro-phenyl)-3-methyl-oxirane

Guidance literature:

With iodosylbenzene; chromium binaphthyl Schiff base complex supported on MCM-41; In toluene; at 20 ℃; Further Variations:; catalyst content; Product distribution;

DOI:10.1039/a905313a

Reference yield:

4-chlorobenzaldehyde (104-88-1) → trans-2-p-Chlorphenyl-3-methyl-oxiran (885318-84-3)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / dioxane; H₂O / Heating

2: E_. coli JM₁₀₉ (pTAB₁₉) / 2,2,4-trimethyl-pentane / 30 °C

With E_. coli JM₁₀₉ (pTAB₁₉); potassium carbonate; In 1,4-dioxane; 2,2,4-trimethylpentane; water;

DOI:10.1016/j.tetasy.2006.01.009

upstream raw materials:

cis-1-phenyl-1-propylene

E-1-(4-chlorophenyl)-1-propene

4-chlorobenzaldehyde