1879-53-4

Basic information

• Product Name: Benzene, 1-chloro-4-(1E)-1-propenyl-
• Synonyms: 4-CHLORO METHYL STYRENE
• CAS NO: 1879-53-4
• Molecular Formula: C9H9Cl
• Molecular Weight: 152.623
• Mol File: 1879-53-4.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-(1E)-1-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-(1E)-1-propenyl-(1879-53-4)
• EPA Substance Registry System: Benzene, 1-chloro-4-(1E)-1-propenyl-(1879-53-4)

Safety Data

• Hazardous Substances Data: 1879-53-4(Hazardous Substances Data)

Upstream product

• 6285-05-8 4'-chloropropiophenone 
• 1745-18-2 1-allyl-4-chlorobenzene 
• 1073-67-2 4-vinylbenzyl chloride 
• 917-54-4 methyllithium 
• 74-88-4 methyl iodide 
• 106-39-8 bromochlorobenzene 
• 637-87-6 1-Chloro-4-iodobenzene 
• 1879-52-3 cis-4-chloro-β-methylstyrene 
• 104-88-1 4-chlorobenzaldehyde 
• 29125-75-5 p-chloro(methylstyrene) 
• 126918-29-4 2-chloro-1-(4-chlorophenyl)propan-1-one 
• 29645-00-9 4-Chlorophenylbutyric acid 
• 513-35-9 2-methyl-but-2-ene 
• 6336-44-3 (E)-propenylboronic acid 

Downstream Products

• 1616356-65-0 N-(1-(4-chlorophenyl)propan-2-yl)-1,1,1-trifluoromethanesulfonamide 

Relevant articles and documents

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Facile Synthesis of Chiral Arylamines, Alkylamines and Amides by Enantioselective NiH-Catalyzed Hydroamination

Regio- and enantioselective hydroarylamination, hydroalkylamination and hydroamidation of styrenes have been developed by NiH catalysis with a simple bioxazoline ligand under mild conditions. A wide range of enantioenriched benzylic arylamines, alkylamines and amides can be easily accessed by nitroarenes, hydroxylamines and dioxazolones, respectively as amination reagents. The chiral induction in these reactions is proposed to proceed through an enantiodifferentiating syn-hydronickellation step.

A donor-acceptor complex enables the synthesis of: E -olefins from alcohols, amines and carboxylic acids

Olefins are prevalent substrates and functionalities. The synthesis of olefins from readily available starting materials such as alcohols, amines and carboxylic acids is of great significance to address the sustainability concerns in organic synthesis. Metallaphotoredox-catalyzed defunctionalizations were reported to achieve such transformations under mild conditions. However, all these valuable strategies require a transition metal catalyst, a ligand or an expensive photocatalyst, with the challenges of controlling the region- and stereoselectivities remaining. Herein, we present a fundamentally distinct strategy enabled by electron donor-acceptor (EDA) complexes, for the selective synthesis of olefins from these simple and easily available starting materials. The conversions took place via photoactivation of the EDA complexes of the activated substrates with alkali salts, followed by hydrogen atom elimination from in situ generated alkyl radicals. This method is operationally simple and straightforward and free of photocatalysts and transition-metals, and shows high regio- and stereoselectivities.