(9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

Base Information

Chemical Name:(9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester
CAS No.:135944-27-3
Molecular Formula:C₅₃H₅₇N₆O₈P
Molecular Weight:937.045
Hs Code.:

(9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

Synonyms:

Suppliers and Price of (9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

There total 6 articles about (9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 135944-27-3,135944-32-0
(9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: 93 percent / pyridine / 18 h

3: 1H-tetrazole / CH₂Cl₂; acetonitrile / 0.67 h

With pyridine; 1H-tetrazole; In dichloromethane; acetonitrile;
DOI:10.1021/jo00020a028

Reference yield:

: 2140-79-6
2'-O-methyl adenosine

: 135944-27-3,135944-32-0
(9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: 93 percent / pyridine / 18 h

3: 1H-tetrazole / CH₂Cl₂; acetonitrile / 0.67 h

With pyridine; 1H-tetrazole; In dichloromethane; acetonitrile;
DOI:10.1021/jo00020a028

Reference yield:

: 135944-25-1
2'-O-methyl-6-N-(9-fluorenylmethoxycarbonyl)adenosine

: 135944-27-3,135944-32-0
(9-{(2R,3R,4R,5R)-4-(Diisopropylamino-methoxy-phosphanyloxy)-3-methoxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / pyridine / 18 h

2: 1H-tetrazole / CH₂Cl₂; acetonitrile / 0.67 h

With pyridine; 1H-tetrazole; In dichloromethane; acetonitrile;
DOI:10.1021/jo00020a028