ethyl 2-amino-4-methoxybenzoate

Base Information

• Chemical Name: ethyl 2-amino-4-methoxybenzoate
• CAS No.: 103096-05-5
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.218
• Mol file: 103096-05-5.mol

Synonyms:

Chemical Property of ethyl 2-amino-4-methoxybenzoate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C

Purity/Quality:

98% ^*data from raw suppliers

ETHYL-2-AMINO-4-METHOXYBENZOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 2-amino-4-methoxybenzoate

There total 5 articles about ethyl 2-amino-4-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

ethanol (64-17-5) + 4-methoxyanthranilic acid (4294-95-5) → 2-amino-4-methoxy-benzoic acid ethyl ester (103096-05-5)

Guidance literature:

With hydrogenchloride; Heating;

Reference yield:

4-methoxy-2-nitro-benzoic acid ethyl ester (13324-13-5) → 2-amino-4-methoxy-benzoic acid ethyl ester (103096-05-5)

Guidance literature:

With nickel; at 100 ℃; under 88260.9 Torr; Hydrogenation;

Reference yield:

6-methoxyisatin (52351-75-4) → 2-amino-4-methoxy-benzoic acid ethyl ester (103096-05-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / aq. NaOH, 30percent H₂O₂ / 24 h / Ambient temperature

2: 52 percent / HCl / Heating

With hydrogenchloride; sodium hydroxide; dihydrogen peroxide;

upstream raw materials:

4-methoxy-2-nitro-benzoic acid ethyl ester

ethanol

4-methoxyanthranilic acid

6-methoxyisatin

Downstream raw materials:

ethyl 4-methoxy-2-(4-methylphenylsulfonamido)benzoate

6-iodo-7-(methyloxy)-4(1H)-quinazolinone

Refernces