2-(2-((tert-Butoxycarbonyl)amino)phenyl)acetic acid

Base Information

Chemical Name:2-(2-((tert-Butoxycarbonyl)amino)phenyl)acetic acid
CAS No.:135807-51-1
Molecular Formula:C13H17NO4
Molecular Weight:251.282
Hs Code.:2924299090
European Community (EC) Number:832-475-2
DSSTox Substance ID:DTXSID10591494
Wikidata:Q82485271
Mol file:135807-51-1.mol

Synonyms:135807-51-1;2-(2-((tert-Butoxycarbonyl)amino)phenyl)acetic acid;BOC-(aminophenyl)acetic acid;boc-(2-aminophenyl)acetic acid;2-[2-(Boc-amino)phenyl]acetic Acid;2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]acetic acid;{2-[(tert-butoxycarbonyl)amino]phenyl}acetic acid;MFCD09750482;2-(2-(BOC-amino)phenyl)acetic acid;Boc-2-aminophenylacetic acid;SCHEMBL1162987;2-(2-{[(tert-butoxy)carbonyl]amino}phenyl)acetic acid;DTXSID10591494;FURUSGMMMFSWDW-UHFFFAOYSA-N;AKOS005073822;SS-3824;s10526;SY023397;(2-tert-butoxycarbonylaminophenyl)acetic acid;EN300-112046;A886931;2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticacid;F2199-0310;Z992494258

Suppliers and Price of 2-(2-((tert-Butoxycarbonyl)amino)phenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticAcid
50mg
$ 45.00

Matrix Scientific
BOC-(aminophenyl)acetic acid >95%
1g
$ 59.00

Matrix Scientific
BOC-(aminophenyl)acetic acid >95%
500mg
$ 38.00

Crysdot
2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticacid 95+%
25g
$ 602.00

Crysdot
2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticacid 95+%
10g
$ 301.00

Chemenu
2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticacid 95%
5g
$ 189.00

Chemenu
2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticacid 95%
10g
$ 284.00

Chemenu
2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticacid 95%
25g
$ 568.00

Biosynth Carbosynth
Boc-(2-aminophenyl)acetic acid
5 g
$ 552.00

Biosynth Carbosynth
Boc-(2-aminophenyl)acetic acid
1 g
$ 215.70

Total 14 raw suppliers

Chemical Property of 2-(2-((tert-Butoxycarbonyl)amino)phenyl)acetic acid

Chemical Property:

Boiling Point:355.6±25.0 °C(Predicted)
PKA:4.19±0.10(Predicted)
PSA：75.63000
Density:1.220±0.06 g/cm3(Predicted)
LogP:2.73370
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:251.11575802
Heavy Atom Count:18
Complexity:309

Purity/Quality:

97% ^*data from raw suppliers

2-(2-((tert-Butoxycarbonyl)amino)phenyl)aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC=CC=C1CC(=O)O

Technology Process of 2-(2-((tert-Butoxycarbonyl)amino)phenyl)acetic acid

There total 3 articles about 2-(2-((tert-Butoxycarbonyl)amino)phenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 3342-78-7
2-(2-aminophenyl)acetic acid

: 135807-51-1
2-(2-((tert-butoxycarbonyl)amino)phenyl)acetic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 6h;
DOI:10.1039/c8ob00642c

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 3740-52-1
2-(2-nitrophenyl)acetic acid

: 135807-51-1
2-(2-((tert-butoxycarbonyl)amino)phenyl)acetic acid

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; sodium hydroxide; palladium;

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 74965-31-4
N-(tert-butoxycarbonyl)-o-toluidine

: 135807-51-1
2-(2-((tert-butoxycarbonyl)amino)phenyl)acetic acid

Guidance literature:: With sec.-butyllithium; Multistep reaction; 1) THF, cyclohexane, -40 to -20 deg C, 2) -40 deg C, 1 min;
DOI:10.1055/s-1991-26597