Ethanediimidoyl dichloride, bis(2-methylphenyl)-

Base Information

• Chemical Name: Ethanediimidoyl dichloride, bis(2-methylphenyl)-
• CAS No.: 135850-46-3
• Molecular Formula: C16H14Cl2N2
• Molecular Weight: 305.207
• DSSTox Substance ID: DTXSID70462070
• Nikkaji Number: J1.102.639G
• Mol file: 135850-46-3.mol

Synonyms:Ethanediimidoyl dichloride, bis(2-methylphenyl)-;135850-46-3;DTXSID70462070;AKOS032962529

Chemical Property of Ethanediimidoyl dichloride, bis(2-methylphenyl)-

Chemical Property:

• XLogP3: 6.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 304.0534038
• Heavy Atom Count: 20
• Complexity: 343

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1N=C(C(=NC2=CC=CC=C2C)Cl)Cl

Technology Process of Ethanediimidoyl dichloride, bis(2-methylphenyl)-

There total 2 articles about Ethanediimidoyl dichloride, bis(2-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-bis(o-tolyl)oxamide (3299-62-5) → N,N'-bis(2-methylphenyl)ethane-bis(imidoyl) dichloride (135850-46-3)

Guidance literature:

With phosphorus pentachloride; at 100 ℃;

DOI:10.1111/1468-0289.00174

Reference yield:

phosphorus pentachloride (10026-13-8,874483-75-7) + N,N'-bis(o-tolyl)oxamide (3299-62-5) → N,N'-bis(2-methylphenyl)ethane-bis(imidoyl) dichloride (135850-46-3)

Guidance literature:

at 100 ℃;

DOI:10.1111/1468-0289.00174

Reference yield: 78.0%

N,N'-bis(2-methylphenyl)ethane-bis(imidoyl) dichloride (135850-46-3) + ethyl 2-sulfanylacetate (623-51-8) → ethyl 5-hydroxy-4-thioxo-2,3-bis(o-tolylamino)-4H-thiopyran-6-carboxylate

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃; for 62h;

DOI:10.1021/jo052450l

upstream raw materials:

N,N'-bis(o-tolyl)oxamide

phosphorus pentachloride

Downstream raw materials:

7-methyl-1H-indole-2,3-dione

N,N'-bis(o-tolyl)oxamide

N,N',N'',N'''-tetra-o-tolyl-oxalamidine