(R)-N,N-dimethyl-3-phenylbutanamine

Base Information

• Chemical Name: (R)-N,N-dimethyl-3-phenylbutanamine
• CAS No.: 39206-52-5
• Molecular Formula: C₁₂H₁₉N
• Molecular Weight: 177.29
• Mol file: 39206-52-5.mol

Synonyms:

Chemical Property of (R)-N,N-dimethyl-3-phenylbutanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-N,N-dimethyl-3-phenylbutanamine

There total 13 articles about (R)-N,N-dimethyl-3-phenylbutanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-N,N-dimethyl-3-phenylbut-2-en-1-amine (82822-01-3) → (R/S)-N,N-dimethyl-(3-phenylbutyl)amine (36617-84-2,39206-52-5,86437-06-1)

Guidance literature:

With hydrogen; In ethanol; at 20 ℃; for 30h;

DOI:10.1016/j.bmc.2016.10.005

Reference yield: 88.0%

3-Phenylbutyraldehyde (16251-77-7) + dimethyl amine (124-40-3) → (R/S)-N,N-dimethyl-(3-phenylbutyl)amine (36617-84-2,39206-52-5,86437-06-1)

Guidance literature:

With hydrogen; In water; at 130 ℃; for 20h; under 33753.4 Torr; Autoclave;

DOI:10.1039/c9sc04963k

Reference yield: 83.0%

C14H24BNO2 (1356941-13-3) → (R/S)-N,N-dimethyl-(3-phenylbutyl)amine (36617-84-2,39206-52-5,86437-06-1)

Guidance literature:

C₁₄H₂₄BNO₂; With trimethylsilyl trifluoromethanesulfonate; In acetonitrile; at 0 - 20 ℃;

With water; sodium hydroxide; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol2031203

upstream raw materials:

α-((N,N-dimethylamino)ethyl)styrene

1-bromo-3-phenylbutane

dimethyl amine

water

Downstream raw materials:

1-Dimethylamino-3-phenylbutan-N-oxid

3-phenylbut-1-ene

(R)-3-phenyl-1-butene