2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane

Base Information

Chemical Name:2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane
CAS No.:1190197-97-7
Molecular Formula:C₄₃H₇₉NO₂
Molecular Weight:642.106
Hs Code.:

Synonyms:

Suppliers and Price of 2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
DLin-KC2-DMA >98%
100 mg
$ 1000.00

DC Chemicals
DLin-KC2-DMA >98%
250 mg
$ 1800.00

DC Chemicals
DLin-KC2-DMA >98%
25 mg
$ 550.00

Biorbyt Ltd
DLin-KC2-DMA >98%
250 mg
$ 2691.10

Biorbyt Ltd
DLin-KC2-DMA >98%
100 mg
$ 1504.50

Biorbyt Ltd
DLin-KC2-DMA >98%
25 mg
$ 838.10

Total 26 raw suppliers

Chemical Property of 2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane

Chemical Property:

Boiling Point:668.1±40.0 °C(Predicted)
Density:0.885±0.06 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

DLin-KC2-DMA >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description DLin-KC2-DMA is a useful ionizable lipid for siRNA delivery. It was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates.

Technology Process of 2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane

There total 5 articles about 2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1190203-56-5
2,2-dilinoleyl-4-(2-methanesulfonylethyl)-[1,3]-dioxolane

: 124-40-3
dimethyl amine

: 1190197-97-7
2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 144h; Inert atmosphere;

Reference yield:

: 1169768-30-2
dilinoleyl ketone

: 1190197-97-7
2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane

Guidance literature:: Multi-step reaction with 3 steps

1: pyridinium p-toluenesulfonate / toluene / Inert atmosphere; Reflux; Dean-Stark tube

2: triethylamine / dichloromethane / 20 °C / Inert atmosphere

3: tetrahydrofuran / 144 h / 20 °C / Inert atmosphere

With pyridinium p-toluenesulfonate; triethylamine; In tetrahydrofuran; dichloromethane; toluene;

Reference yield:

: 1190203-55-4
2,2-dilinoleyl-4-(2-hydroxyethyl)-[1,3]-dioxolane

: 1190197-97-7
2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C / Inert atmosphere

2: tetrahydrofuran / 144 h / 20 °C / Inert atmosphere

With triethylamine; In tetrahydrofuran; dichloromethane;