1,4-dihydro-7-nitro-1,4-epoxynaphthalene

Base Information

• Chemical Name: 1,4-dihydro-7-nitro-1,4-epoxynaphthalene
• CAS No.: 784210-36-2
• Molecular Formula: C₁₀H₇NO₃
• Molecular Weight: 189.17
• Mol file: 784210-36-2.mol

Synonyms:

Chemical Property of 1,4-dihydro-7-nitro-1,4-epoxynaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-dihydro-7-nitro-1,4-epoxynaphthalene

There total 2 articles about 1,4-dihydro-7-nitro-1,4-epoxynaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

furan (110-00-9) + (4-nitrophenyl)(2,4,6-trimethylphenyl)iodonium tosylate (1240390-04-8) → 4-tert-butoxy-1-nitrobenzene (2109-72-0) + 1,4-dihydro-7-nitro-1,4-epoxynaphthalene (784210-36-2)

Guidance literature:

With sodium t-butanolate; 1,3,5-trimethyl-benzene; In toluene; at 20 ℃; for 1h; Reagent/catalyst; Sealed tube;

DOI:10.1021/acs.orglett.1c01534

Reference yield:

p-nitrobenzene iodide (636-98-6) → 4-tert-butoxy-1-nitrobenzene (2109-72-0) + 1,4-dihydro-7-nitro-1,4-epoxynaphthalene (784210-36-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 3-chloro-benzenecarboperoxoic acid / acetonitrile; water / 0.5 h / 77 °C

1.2: 3 h / 77 °C

2.1: 1,3,5-trimethyl-benzene; sodium t-butanolate / toluene / 1 h / 20 °C / Sealed tube

With 3-chloro-benzenecarboperoxoic acid; sodium t-butanolate; 1,3,5-trimethyl-benzene; In water; toluene; acetonitrile;

DOI:10.1021/acs.orglett.1c01534

Reference yield:

1,4-dihydro-7-nitro-1,4-epoxynaphthalene (784210-36-2) → 7-nitronaphthalen-1-ol (19256-82-7) + 6-nitro-1-naphthalenol (38397-06-7)

Guidance literature:

With hydrogenchloride; In methanol; Yield given. Title compound not separated from byproducts; Heating;

DOI:10.1016/S0040-4020(01)87413-5

upstream raw materials:

furan

(4-nitrophenyl)(2,4,6-trimethylphenyl)iodonium tosylate

p-nitrobenzene iodide

Downstream raw materials:

7-nitronaphthalen-1-ol

6-nitro-1-naphthalenol