HOCHC₂N(CH₃)3C₆H₅O₄C(C₆H₅)3

Base Information

• Chemical Name: HOCHC₂N(CH₃)3C₆H₅O₄C(C₆H₅)3
• CAS No.: 872201-69-9
• Molecular Formula: C₃₁H₃₁NO₅
• Molecular Weight: 497.591
• Mol file: 872201-69-9.mol

Synonyms:

Chemical Property of HOCHC₂N(CH₃)3C₆H₅O₄C(C₆H₅)3

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of HOCHC₂N(CH₃)3C₆H₅O₄C(C₆H₅)3

There total 1 articles about HOCHC₂N(CH₃)3C₆H₅O₄C(C₆H₅)3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-C-methyl-2,3-O-(1-methylethylidene)-5-O-trityl-α-D-ribofuranosyl)acetonitrile (872201-78-0) + Methyl formate (107-31-3) → HOCHC2N(CH3)3C6H5O4C(C6H5)3 (872201-69-9)

Guidance literature:

2-(2-C-methyl-2,3-O-(1-methylethylidene)-5-O-trityl-α-D-ribofuranosyl)acetonitrile; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h;

Methyl formate; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Further stages.;

DOI:10.1016/j.bmc.2007.05.020

Reference yield:

HOCHC2N(CH3)3C6H5O4C(C6H5)3 (872201-69-9) + 2-aminoacetonitrile hydrochloride (6011-14-9) → NCCH2NHCHC2N(CH3)3C6H5O4C(C6H5)3

Guidance literature:

With sodium acetate; In methanol; at 20 ℃; for 72h;

DOI:10.1016/j.bmc.2007.05.020

Reference yield:

HOCHC2N(CH3)3C6H5O4C(C6H5)3 (872201-69-9) + chloroacetonitrile (107-14-2) → NCCH2OCHC2N(CH3)3C6H5O4C(C6H5)3

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmc.2007.05.020

upstream raw materials:

2-(2-C-methyl-2,3-O-(1-methylethylidene)-5-O-trityl-α-D-ribofuranosyl)acetonitrile

Methyl formate