5-Cyclopropylcytosine

Base Information

• Chemical Name: 5-Cyclopropylcytosine
• CAS No.: 137937-76-9
• Molecular Formula: C7H9N3O
• Molecular Weight: 151.168
• UNII: L4LWE3PT05
• Nikkaji Number: J433.742E
• Wikidata: Q27282699
• Mol file: 137937-76-9.mol

Synonyms:5-cyclopropylcytosine;5-Cyclopropyl-cytosine;UNII-L4LWE3PT05;L4LWE3PT05;2(1H)-Pyrimidinone, 6-amino-5-cyclopropyl-;137937-76-9;SCHEMBL4879962;6-Amino-5-cyclopropylpyrimidin-2(1H)-one;Q27282699

Chemical Property of 5-Cyclopropylcytosine

Chemical Property:

• XLogP3: -0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 151.074561919
• Heavy Atom Count: 11
• Complexity: 263

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1C2=C(NC(=O)N=C2)N

Technology Process of 5-Cyclopropylcytosine

There total 1 articles about 5-Cyclopropylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tri-n-butyl-cyclopropyltin (17857-70-4) + 5-Bromo-2,4-O,N-bis-trimethylsilylcytosine (50271-92-6) → Cytosine (71-30-7) + 5-Cyclopropylcytosine (137937-76-9)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; water; Yield given. Multistep reaction; 1.) 110 deg C, 72 h, 2.) acetone, r.t., 1 h;

DOI:10.1002/jhet.5570280629

upstream raw materials:

tri-n-butyl-cyclopropyltin

5-Bromo-2,4-O,N-bis-trimethylsilylcytosine

Refernces