17857-70-4

Usage

Uses

Used in Organic Chemistry:
Cyclopropyltributylstannane is used as a reagent for a variety of organic reactions, facilitating the formation of new chemical bonds and structures. Its ability to generate cyclopropylcarbinyl radicals makes it a valuable component in radical reactions, contributing to the synthesis of complex organic molecules.
Used in Synthesis of Organic Compounds:
In the realm of organic synthesis, Cyclopropyltributylstannane serves as a key intermediate, aiding in the production of a diverse range of organic compounds. Its unique structure and reactivity enable the creation of molecules with specific properties and functions, catering to various industrial and research needs.
Used as a Ligand in Coordination Chemistry:
Beyond its applications in organic synthesis, Cyclopropyltributylstannane also plays a role in coordination chemistry, where it acts as a ligand. Its coordination to metal centers can influence the properties and reactivity of the resulting complexes, opening up new avenues for research and application in areas such as catalysis and materials science.

InChI:InChI=1/3C4H9.C3H5.Sn/c3*1-3-4-2;1-2-3-1;/h3*1,3-4H2,2H3;1H,2-3H2;/rC15H32Sn/c1-4-7-12-16(13-8-5-2,14-9-6-3)15-10-11-15/h15H,4-14H2,1-3H3

Upstream product

• 1461-22-9 tributyltin chloride 
• 23719-80-4 cyclopropylmagnesium bromide 
• 4333-56-6 cyclopropyl bromide 

Downstream Products

• 66-22-8 uracil 
• 59698-20-3 5-cyclopropyl-pyrimidin-2,4-(1H,3H)-dione 
• 59968-56-8 5-cyclopropyl-2,4-bis(trimethylsilyloxy)pyrimidine 
• 10457-14-4 O,O'-bis-(trimethylsilyl)uracil 
• 71-30-7 Cytosine 
• 137937-76-9 5-Cyclopropylcytosine 
• 143324-68-9 (5-Cyclopropyl-2-trimethylsilanyloxy-pyrimidin-4-yl)-trimethylsilanyl-amine 
• 18037-10-0 2,4-O,N-bis(trimethylsilyl)cytosine 
• 1038508-87-0 2-cyclopropyl-5-(4-fluoro-phenyl)-thiazole-4-carboxylic acid methyl ester 
• 1416732-74-5 C₁₇H₁₃F₄NO 
• 1038508-84-7 methyl 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylate 
• 171489-89-7 methyl (E) 6-(6-cyclopropyl-1,3-dihydro-7-methyl-3-oxo-4-p-toluenesulfonyloxyisobenzofuran-5-yl)-4-methyl-4-hexenoate 

Relevant academic research and scientific papers

2-CYCLOPROPYL-THIAZOLE DERIVATIVES

The invention relates to selected 2-cyclopropyl-thiazole derivatives of the formula (I) wherein B, Y and R1 are as described in the description; to salts and especially pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.

ORGANIC COMPOUNDS

The present invention provides a compound of formula (I):said compound is inhibitor of aldosterone synthase, and thus can be employed for the treatment of a disorder or disease mediated by aldosterone synthase. Accordingly, the compound of formula I can be used in treatment of hypokalemia, hypertension, congestive heart failure, renal failure, in particular, chronic renal failure, restenosis, atherosclerosis, syndrome X, obesity, nephropathy, post-myocardial infarction, coronary heart diseases, increased formation of collagen, cardiac fibrosis and remodeling following hypertension and endothelial dysfunction. Finally, the present invention also provides a pharmaceutical composition.

6-substituted mycophenolic acid and derivatives

The disclosed 6-substituted derivatives of mycophenolic acid are therapeutic agents advantageous in the treatment of disease states indicated for mycophenolic acid and/or mycophenolate mofetil.