19-noretiocholanolone glucuronide

Base Information

• Chemical Name: 19-noretiocholanolone glucuronide
• CAS No.: 294213-87-9
• Molecular Formula: C₂₄H₃₆O₈
• Molecular Weight: 452.545
• Mol file: 294213-87-9.mol

Synonyms:

Chemical Property of 19-noretiocholanolone glucuronide

Chemical Property:

• Boiling Point: 661.5±55.0 °C(Predicted)
• PKA: 2.82±0.70(Predicted)
• Density: 1.36±0.1 g/cm3(Predicted)

Purity/Quality:

95% ^*data from raw suppliers

19-Noretiocholanolone glucuronide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 19-Noretiocholanolone Glucuronide is the glucuronide conjugate of 19-Noretiocholanolone (N675200), the main metabolite of nandrolone (N315000).

Technology Process of 19-noretiocholanolone glucuronide

There total 5 articles about 19-noretiocholanolone glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

19-nortestosterone (434-22-0) + UDP-glucuronic acid (2616-64-0) → estr-4-en-3-one-17β-O-glucuronide (131749-24-1) + 3α-hydroxy-5α-estran-17-one glucuronide (294213-86-8,294213-87-9) + 3α-hydroxy-5β-estran-17-one glucuronide (294213-87-9)

Guidance literature:

With liver microsomes from Aroclor 1254-induced male Wistar rat; In methanol; phosphate buffer; at 37 ℃; pH=7.4;

DOI:10.1016/j.steroids.2007.10.008

Reference yield: 77.0%

19-nortestosterone (434-22-0) + UDP-glucuronic acid (2616-64-0) → estr-4-en-3-one-17β-O-glucuronide (131749-24-1) + 3α-hydroxy-5α-estran-17-one glucuronide (294213-86-8,294213-87-9) + 3α-hydroxy-5β-estran-17-one glucuronide (294213-87-9)

Guidance literature:

With liver microsomes from Aroclor 1254-induced male Wistar rat; In methanol; phosphate buffer; at 37 ℃; pH=7.4;

DOI:10.1016/j.steroids.2007.10.008

Reference yield:

(2S,3S,4S,5R,6R)-3,4,5-Triacetoxy-6-((3R,5S,8R,9R,10S,13S,14S)-13-methyl-17-oxo-hexadecahydro-cyclopenta[a]phenanthren-3-yloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester → 3α-hydroxy-5α-estran-17-one glucuronide (294213-86-8,294213-87-9)

Guidance literature:

With sodium hydroxide; In methanol;

DOI:10.1002/jms.117

upstream raw materials:

19-Norandrosterone

(3R,4S,5S,6S)-2-bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

19-nortestosterone

UDP-glucuronic acid

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