Technology Process of C19H14F3NO2
There total 4 articles about C19H14F3NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium periodate; ruthenium(III) chloride trihydrate;
In
tetrachloromethane; water; acetonitrile;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1007/s00726-011-0881-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 0.17 h / -78 - 0 °C / Inert atmosphere
1.2: -78 °C / Inert atmosphere
2.1: Raney nickel / tetrahydrofuran / Inert atmosphere
3.1: sodium periodate; ruthenium(III) chloride trihydrate / tetrachloromethane; water; acetonitrile / 2 h / 20 °C / Inert atmosphere
With
sodium periodate; n-butyllithium; ruthenium(III) chloride trihydrate; diisopropylamine;
In
tetrahydrofuran; tetrachloromethane; water; acetonitrile;
DOI:10.1007/s00726-011-0881-7
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene / Heating
2.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 0.17 h / -78 - 0 °C / Inert atmosphere
2.2: -78 °C / Inert atmosphere
3.1: Raney nickel / tetrahydrofuran / Inert atmosphere
4.1: sodium periodate; ruthenium(III) chloride trihydrate / tetrachloromethane; water; acetonitrile / 2 h / 20 °C / Inert atmosphere
With
sodium periodate; n-butyllithium; ruthenium(III) chloride trihydrate; diisopropylamine;
In
tetrahydrofuran; tetrachloromethane; water; toluene; acetonitrile;
1.1: Aza-Wittig reaction;
DOI:10.1007/s00726-011-0881-7
