(4-Chlorobenzyl)trimethylsilane

Base Information

• Chemical Name: (4-Chlorobenzyl)trimethylsilane
• CAS No.: 17876-99-2
• Molecular Formula: C10H15 Cl Si
• Molecular Weight: 198.768
• NSC Number: 45069
• DSSTox Substance ID: DTXSID70939116
• Nikkaji Number: J2.071.075F
• Wikidata: Q82915560
• Mol file: 17876-99-2.mol

Synonyms:17876-99-2;(4-Chlorobenzyl)trimethylsilane;NSC45069;DTXSID70939116;NSC-45069;[(4-Chlorophenyl)methyl](trimethyl)silane

Chemical Property of (4-Chlorobenzyl)trimethylsilane

Chemical Property:

• Vapor Pressure: 0.163mmHg at 25°C
• Boiling Point: 220.9°Cat760mmHg
• Flash Point: 88.1°C
• Density: 0.979g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 198.0631547
• Heavy Atom Count: 12
• Complexity: 131

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)CC1=CC=C(C=C1)Cl

Technology Process of (4-Chlorobenzyl)trimethylsilane

There total 12 articles about (4-Chlorobenzyl)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

chloro-trimethyl-silane (75-77-4) + 1-Chloro-4-(chloromethyl)benzene (104-83-6) → (4-chlorobenzyl)trimethylsilane (17876-99-2)

Guidance literature:

With tetraethylammonium tosylate; In N,N-dimethyl-formamide; electrochemical reduction using diaphragm;

DOI:10.1246/cl.1985.463

Reference yield: 81.0%

4-chlorophenyl trifluoromethanesulfonate (29540-84-9) + (trimethylsilyl)methylzinc chloride (82049-86-3) → (4-chlorobenzyl)trimethylsilane (17876-99-2)

Guidance literature:

With di-μ-iodobis(tri-t-butylphosphino)dipalladium(l); In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 0.166667h; chemoselective reaction;

DOI:10.1002/anie.201808386

Reference yield: 76.0%

chloro-trimethyl-silane (75-77-4) → (4-chlorobenzyl)trimethylsilane (17876-99-2)

Guidance literature:

With magnesium; In tetrahydrofuran; for 2h; Reflux;

DOI:10.1002/anie.201202794

upstream raw materials:

methyl magnesium iodide

(4-Chlorobenzyl)trichlorosilane

chloro-trimethyl-silane

4-chlorobenzylmagnesium chloride

Downstream raw materials:

trimethyl-(4-trimethylsilanyl-benzyl)-silane

4-<(trimethylsilyl)methyl>benzoic acid

4-chlorobenzyl methyl ether

3-(4-chlorophenylmethyl)-1-cyanonaphthalene