5-Chloro-1,3-dimethoxy-2-nitrobenzene

Base Information

• Chemical Name: 5-Chloro-1,3-dimethoxy-2-nitrobenzene
• CAS No.: 83-21-6
• Molecular Formula: C₈H₈ClNO₄
• Molecular Weight: 217.609
• DSSTox Substance ID: DTXSID501288614
• Nikkaji Number: J160.890H
• Mol file: 83-21-6.mol

Synonyms:83-21-6;SCHEMBL7425270;DTXSID501288614;5-chloro-1,3-dimethoxy-2-nitrobenzene

Chemical Property of 5-Chloro-1,3-dimethoxy-2-nitrobenzene

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 217.0141854
• Heavy Atom Count: 14
• Complexity: 194

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1[N+](=O)[O-])OC)Cl

Technology Process of 5-Chloro-1,3-dimethoxy-2-nitrobenzene

There total 3 articles about 5-Chloro-1,3-dimethoxy-2-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-trichloronitrobenzene (18708-70-8) + sodium methylate (124-41-4) → 1,3,5-trimethoxy-2-nitrobenzene (14227-18-0) + 3,5-dichloro-2-nitroanisole (74672-01-8) + 5-chloro-1,3-dimethoxy-2-nitro-benzene (83-21-6)

Guidance literature:

DOI:10.1039/jr9340001433

Reference yield:

2,4,6-trichloronitrobenzene (18708-70-8) + sodium methylate (124-41-4) → 3,5-dichloro-2-nitroanisole (74672-01-8) + 5-chloro-1,3-dimethoxy-2-nitro-benzene (83-21-6)

Guidance literature:

With methanol; at 120 ℃;

DOI:10.1039/jr9340001433

Reference yield:

3,5-dichloro-2-nitroanisole (74672-01-8) + sodium methylate (124-41-4) → 5-chloro-1,3-dimethoxy-2-nitro-benzene (83-21-6)

Guidance literature:

upstream raw materials:

2,4,6-trichloronitrobenzene

sodium methylate

3,5-dichloro-2-nitroanisole

Downstream raw materials:

1-chloro-3,5-dimethoxy-2,4-dinitro-benzene