4',5-Dihydroxy-7,8-dimethoxyflavone

Base Information

Chemical Name:4',5-Dihydroxy-7,8-dimethoxyflavone
CAS No.:6608-33-9
Molecular Formula:C₁₇H₁₄O₆
Molecular Weight:314.295
Hs Code.:
DSSTox Substance ID:DTXSID601294804
Metabolomics Workbench ID:24448
Nikkaji Number:J302.615I
Wikidata:Q105001026

Synonyms:4',5-Dihydroxy-7,8-dimethoxyflavone;Isoscutellarein 7,8-dimethyl ether;6608-33-9;5,4'-dihydroxy-7,8-dimethoxyflavone;5-hydroxy-2-(4-hydroxyphenyl)-7,8-dimethoxy-4H-chromen-4-one;SCHEMBL6359647;CHEBI:175013;DTXSID601294804;LMPK12111365;5-hydroxy-2-(4-hydroxyphenyl)-7,8-dimethoxychromen-4-one

Suppliers and Price of 4',5-Dihydroxy-7,8-dimethoxyflavone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4',5-Dihydroxy-7,8-dimethoxyflavone

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:314.07903816
Heavy Atom Count:23
Complexity:468

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C2=C(C(=C1)O)C(=O)C=C(O2)C3=CC=C(C=C3)O)OC

Technology Process of 4',5-Dihydroxy-7,8-dimethoxyflavone

There total 6 articles about 4',5-Dihydroxy-7,8-dimethoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6601-67-8
4'-benzyloxy-5,7,8-trimethoxyflavone

: 6608-33-9
5,4′-hydroxy-7,8-dimethoxyflavone

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd-C

2: AlCl₃ / nitrobenzene / Ambient temperature

With aluminium trichloride; hydrogen; palladium on activated charcoal; In nitrobenzene;
DOI:10.1248/cpb.28.717

Reference yield:

: 1486-51-7
p-(benzyloxy)benzoic acid

: 6608-33-9
5,4′-hydroxy-7,8-dimethoxyflavone

Guidance literature:: Multi-step reaction with 5 steps

1: (CF₃CO)2O / benzene / 4 h / Ambient temperature

2: KOH / pyridine / 0.33 h / 110 °C

3: conc. H₂SO₄ / acetic acid / 0.12 h / 110 °C

4: H₂ / Pd-C

5: AlCl₃ / nitrobenzene / Ambient temperature

With potassium hydroxide; aluminium trichloride; sulfuric acid; hydrogen; trifluoroacetic anhydride; palladium on activated charcoal; In pyridine; acetic acid; nitrobenzene; benzene;
DOI:10.1248/cpb.28.717

Reference yield:

: 7507-98-4
1-(2-hydroxy-3,4,6-trimethoxyphenyl)ethanone

: 6608-33-9
5,4′-hydroxy-7,8-dimethoxyflavone

Guidance literature:: Multi-step reaction with 5 steps

1: (CF₃CO)2O / benzene / 4 h / Ambient temperature

2: KOH / pyridine / 0.33 h / 110 °C

3: conc. H₂SO₄ / acetic acid / 0.12 h / 110 °C

4: H₂ / Pd-C

5: AlCl₃ / nitrobenzene / Ambient temperature

With potassium hydroxide; aluminium trichloride; sulfuric acid; hydrogen; trifluoroacetic anhydride; palladium on activated charcoal; In pyridine; acetic acid; nitrobenzene; benzene;
DOI:10.1248/cpb.28.717