1-Fluoro-8-hydroxynaphthalene

Base Information

Chemical Name:1-Fluoro-8-hydroxynaphthalene
CAS No.:383155-01-9
Molecular Formula:C₁₀H₇FO
Molecular Weight:162.163
Hs Code.:
DSSTox Substance ID:DTXSID50469461
Nikkaji Number:J2.792.730K
Wikidata:Q82297194
Mol file:383155-01-9.mol

Synonyms:1-Fluoro-8-hydroxynaphthalene;8-fluoronaphthalen-1-ol;383155-01-9;SCHEMBL4959166;DTXSID50469461;CS-0343266;FT-0731268;Y12618;A937763

Suppliers and Price of 1-Fluoro-8-hydroxynaphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
1-Fluoro-8-hydroxynaphthalene
5g
$ 990.00

Alichem
1-Fluoro-8-hydroxynaphthalene
1g
$ 590.00

Total 4 raw suppliers

Chemical Property of 1-Fluoro-8-hydroxynaphthalene

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:162.048093005
Heavy Atom Count:12
Complexity:160

Purity/Quality:

99%+ ^*data from raw suppliers

1-Fluoro-8-hydroxynaphthalene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)O)C(=CC=C2)F

Technology Process of 1-Fluoro-8-hydroxynaphthalene

There total 5 articles about 1-Fluoro-8-hydroxynaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 13720-52-0
8-fluoronaphthalen-1-ylamine

: 383155-01-9
8-fluoro-1-naphthol

Guidance literature:: With sulfuric acid; sodium nitrite; In water; at 20 ℃; for 0.333333h; Cooling with ice; Inert atmosphere;
DOI:10.1021/acs.joc.9b03217

Reference yield:

: 204-03-5
1H-naphtho[1,8-de][1,2,3]triazine

: 383155-01-9
8-fluoro-1-naphthol

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen fluoride / pyridine / 168 h / 20 °C / Inert atmosphere

2: sodium nitrite; sulfuric acid / water / 0.33 h / 20 °C / Cooling with ice; Inert atmosphere

With sulfuric acid; hydrogen fluoride; sodium nitrite; In pyridine; water;
DOI:10.1021/acs.joc.9b03217

Reference yield:

: 479-27-6
naphthalene-1,8-diamine

: 383155-01-9
8-fluoro-1-naphthol

Guidance literature:: Multi-step reaction with 3 steps

1: sodium nitrite / water; acetic acid / -6 - 10 °C

2: hydrogen fluoride / pyridine / 168 h / 20 °C / Inert atmosphere

3: sodium nitrite; sulfuric acid / water / 0.33 h / 20 °C / Cooling with ice; Inert atmosphere

With sulfuric acid; hydrogen fluoride; sodium nitrite; In pyridine; water; acetic acid;
DOI:10.1021/acs.joc.9b03217